Featured Studies

Adults with recurrent glioblastoma may be eligible for an NIH research study evaluating LMP744, an investigational drug with FDA orphan drug designation for gliomas. The study aims to assess the drug's safety and both its short- and long-term treatment effects.

NIH researchers need volunteers with a health condition that affects how their body handles fats. Adults 18+ with conditions that affect how the body handles fats, like obesity, lipodystrophy, nephrotic syndrome, type 2 diabetes, and fatty liver, may be eligible to participate in a research study looking at how different fats in meals affect fat levels in the blood.

Healthy Volunteers Needed for Nutrition & Heart Health Research. Researchers at the National Institutes of Health are studying how meals with different nutrient levels affect fats in the blood, which may play a role in heart disease and other health conditions.

Dr. Komarow and his team at the National Institutes of Health (NIH) are conducting a clinical research study to better understand how everyday environmental exposures may affect allergic and inflammatory responses in healthy adults. With allergic and inflammatory conditions increasing over time, this study aims to explore how common substances in air, food, and personal care products influence human health.

Dr. Regenold and his team at the National Institutes of Health (NIH) are leading a study to explore an investigational new, non-invasive brain stimulation technique to see if it can safely support people experiencing symptoms of depression.

Dr. Gahl and his team at the National Human Genome Research Institute are seeking volunteers aged 18 and older with primary FSGS to participate in a research study on the effects of an experimental drug, ManNAc, on this disease. The study aims to assess the long-term safety and tolerability of ManNAc and determine whether it can reduce protein in the urine of people with FSGS.

Researchers at the National Institute of Mental Health (NIMH) are studying an investigational drug, HNK, to see if it is effective in treating major depression. If you're 18–70 years old and have major depressive disorder (MDD), you may qualify for this 12- to 14-week inpatient research study.

Researchers at NCI are developing a new investigational treatment known as TNhYP218 CAR T cells to target and kill tumor cells in people with solid tumors and with those that have high levels of mesothelin (MSLN) including mesothelioma. The study team collects immune cells (T cells); the T cells are genetically modified to target and kill tumor cells to potentially shrink the tumor.

Research Study #001854-I to explore the effects of Zemaira® for individuals with eosinophilic esophagitis (EoE). This study aims to understand how people with EoE feel while taking Zemaira® and whether it provides any benefits. By joining this research, you'll have the opportunity to contribute to medical advancements that could improve care for those with EoE. Every patient plays a key role in shaping future treatments and expanding knowledge about this condition. 

To learn how malaria develops in people; how the body's immune system reacts to malaria; and how malaria spreads from people to mosquitoes.