Search all current COVID-19 research studies at the NIH Clinical Center.
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About 1,500 clinical research studies are being conducted at the NIH Clinical Center. There are opportunities for healthy and patient volunteers, including:
Opportunities for Patient Volunteers
- 000078-EI: Ocular Findings and Viral Persistence in Ocular Fluids in COVID-19 Survivors, a Natural History, Observational Study
- 17-C-0049: Research Study Opportunity for Individuals with Rhabdomyosarcoma
- 000115-C: Are you currently being treated for cancer? Researchers want to explore how well cancer patients respond to the vaccine
- 000115-C: Reclutando pacientes con cáncer para un estudio de la vacuna para el COVID-19 - ¿Está usted siendo tratado para el cáncer?
- 20-HG-0090: Genetics of COVID-19 Susceptibility and Manifestations
- 19-HG-0092: New Approaches for Empowering Studies of Asthma in Populations of African Descent
- 18-C-0137: Phase II Clinical Trial of Sunitinib in Sarcomas of the Central Nervous System
- 000102-CC: COVID-19, Chronic Adaptation and Response to Exercise (COVID-CARE): A Randomized Controlled Trial
- 000102-CC: COVID-19, Adaptación crónica y respuesta al ejercicio (COVID-CARE): un ensayo controlado aleatorio
- 11-NR-0014: NIH Cancer Related Fatigue Research Study
- Eye Symptoms in Patients with Confirmed COVID-19 Infection: A Survey Study
- 20-H-0137: Effects of Fixed Dose Flavonoid Isoquercetin on Thrombo-Inflammatory Biomarkers in Subjects with Stable Sickle Cell Disease
- 17-C-0102: Phase II Trial of the Immune Checkpoint Inhibitor Nivolumab in Patients with Select Rare CNS Cancers
- 19-C-0006: A Phase II trial of Nivolumab for IDH-Mutated Gliomas with Hypermutator Phenotype
- 000110-H: Fostamatinib for Hospitalized Adults With COVID-19
- 20-I-0140: A Trial of NT-I7 in COVID-19 (SPESELPIS)
- 19-CH-0071: An Open-Label Phase 3 Study of the Safety and Efficacy of Pegvisomant in Children with Growth Hormone Excess
- 20-CC-0113: Cardiopulmonary Inflammation and Multi-System Imaging During the Clinical Course of COVID-19 Infection in Asymptomatic and Symptomatic Persons
- 17-H-0019: NIH Severe Aplastic Anemia Study
- 20-NR-0003: A Proof-of-Concept Trial on the Effect of Ketamine on Fatigue
- 16-N-0055: The Pathological Basis of MRI Signal Changes in Multiple Sclerosis: A Longitudinal In Vivo-to-Postmortem Study
- 20-DK-0018: NIDDK Research of Prebiotic Fiber Supplements With Metformin in Youths With Type 2 Diabetes
- 20-C-0006: Liver Cancer Clinical Research Study
- 17-DK-0054: The Physiological Responses and Adaptation of Brown Adipose Tissue to Chronic Treatment with Beta-3-Adrenergic Receptor Agonists
- 19-C-0011: A Study for Adults with Recurrent Ependymoma
- 20-C-0001: Trial of MVA-BN-Brachyury Vaccine in Patients with Advanced Cancer
- 17-C-0092: Patients with Colorectal Cancer
- 20-H-0021: Do you know someone with Diamond-Blackfan anemia (DBA)?
- 16-C-0135: Ablative Therapies in Subjects with Hepatocellular Carcinoma or Biliary Tract Carcinomas
- 15-C-0075: A Randomized, Placebo-Controlled Phase II Study of Multi-Epitope TARP Peptide Autologous Dendritic Cell Vaccination in Men with Stage D0 Prostate Cancer
- 19-H-0139: Clonal Hematopoiesis of Indeterminate Potential (CHIP)
- 19-H-0139: Clonal Cytopenia of Undetermined Significance (CCUS)
- 19-H-0100: Best Noninvasive Predictor of Renal Function in Assessing Adult Sickle Nephropathy
- 19-C-0125: Patients with Unresectable Fibrolamellar Hepatocellular Carcinoma
- 20-H-0016: Someone Diagnosed With Chronic Lymphocytic Leukemia or Small Lymphocytic Lymphoma
- 19-C-0094: Patients with Hepatocellular Carcinoma
- 17-C-0082: Are You Diagnosed With Biliary Tract Carcinoma?
- 08-C-0214: A Pilot Study to Evaluate Neuropsychological Outcome Measures and their Relationship with Prognosis in Patients Receiving Radiation Therapy for Brain Metastases
- 19-C-0033: Are You Diagnosed With Hepatocellular Carcinoma (Liver Cancer)?
- 16-C-0151: Evaluation of the Natural History of and Specimen Banking for Patients with Tumors of the Central Nervous System
- 18-H-0012: Have you been diagnosed with Kidney Cancer?
- 17-CC-0111: Pilot Study Characterizing Aerobic Exercise in Women with Systemic Lupus Erythematosus (Exercise SLE Pilot)
- 16-H-0144: Impact of Elastin Mediated Vascular Stiffness on End Organs
- 19-H-0001: Response to the SHINGRIX Varicella Zoster Virus (VZV) Vaccine in Chronic Lymphocytic Leukemia (CLL)
- 18-H-0145: Response to the HEPLISAV-B Hepatitis B Vaccine in Chronic Lymphocytic Leukemia (CLL)
- 19-H-0111: Early Clonal Dynamics During Venetoclax Treatment for Relapsed or Refractory Chronic Lymphocytic Leukemia (CLL)
- 19-DK-0050: The Use of 124-I-PET/CT Whole Body and Lesional Dosimetry in Differentiated Thyroid Cancer
- 19-DK-0072: Non-Alcoholic Fatty Liver Disease, the Hepatic Response to Oral Glucose, and the Effect of Semaglutide (NAFLD HEROES)
- 19-DK-0072: Hígado graso no alcohólico, respuesta hepática a la glucosa oral y efecto de la semaglutida (NAFLD HEROES)
- 14-NR-0032: Have you recently experienced a head injury?
- 10-DK-0102: Clinical and Genetic Studies in Familial Non-Medullary Thyroid Cancer
- 18-CH-0120: Osteogenesis Imperfecta study seeking patient volunteers
- 77-DK-0096: Studies on Thyroid Nodules and Thyroid Cancer
- 19-C-0040: Do you have a genetic risk factor for Prostate Cancer?
- 01-N-0206: Phenotype/Genotype Correlations in Movement Disorders
- 13-H-0051: Bronchodilator Effects of Nebulized Versus Inhaled Albuterol in Subjects With Lymphangioleiomyomatosis
- 12-CC-0211: Pulmonary Arterial Hypertension (PAH) Clinical Trial Seeking Participants
- 13-AR-0056: Stopping Tumor Necrosis Factor-Alpha Inhibitors in Rheumatoid Arthritis
- 85-I-0127: Treatment of Cysticercosis Including Neurocysticercosis With Praziquantel, Albendazole and Other Novel Treatment Modalities
- 07-H-0005: Pilot Study of Topical Dexamethasone 0.01% Solution for Prevention of Oral Chronic Graft Versus Host Disease
- 18-H-0146: Genotype -Phenotype Correlation of PKLR Variants with Pyruvate Kinase, 2,3-Diphosphglycerate and ATP Activities in Red Blood Cells of Patients with Sickle Cell Disease
- 14-AA-0181: Have you tried to stop drinking, but can't?
- 17-H-0091: Stem Cell Transplant for Severe Aplastic Anemia and Myelodysplastic Syndrome
- 15-I-0162: Natural History and Genetics of Food Allergy and Related Conditions
- 17-C-0074: Alveolar Soft Part Sarcoma Clinical Trial
- 12-C-0107: Do you have smoldering multiple myeloma (SMM)?
- 16-AA-0080: Is alcohol affecting your life?
- 17-H-0121: Patients with Fanconi Anemia
- 17-H-0162: Mobile Health Physical Activity Intervention
- 17-AA-0114: Brain Dopaminergic signaling in opiod use disorders (OUD)
- 17-AA-0093: Brain-Gut connection and alcohol use
- 13-H-0194: Heart Disease and Diabetes
- 18-I-0030: Persons Living with HIV
- 13-H-0194: Coronary Artery Disease
- 96-H-0100: Adults with COPD or cystic fibrosis needed
- 16-N-0058: Have you recovered from Lyme disease? (ages 18-60)
- 16-N-0058: Do you have Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS) after recovering from an infection?
- 17-DK-0013: African American Youth needed for type 2 diabetic study
- 18-H-0004: Telomere-Related Diseases
- Williams Syndrome
- 17-AA-0152: Do You Have an Alcohol Use Disorder and Want Treatment?
- 17-C-0043: Hereditary Stomach Cancer
- 17-H-0118: Study for Chronic Lymphocytic Leukemia (CLL)
- 14-AA-0192: Research on Alcohol
- 17-I-0101: Crohn's Disease
- 96-H-0100: Have You Been Diagnosed with Cystic Fibrosis?
- 17-C-0034: Glioblastoma (GBM)
- 17-N-0076: Do you have Parkinson's Disease?
- 17-C-0044: Studies for Stomach Cancer
- 17-C-0070: HIPEC for Stomach Cancer
- 15-D-0129: Do You Have Dry Mouth Due to Radiation Therapy?
- 15-AA-0127: Alcohol Use and Early Life Stress
- 12-HG-0181: Sex Chromosome Variants
- 92-I-0125: Lymph Node Study
- 15-AR-0060: Do you have Lupus?
- 99-H-0076: Do You Have Asthma?
- 94-I-0073: Inherited Immune System Diseases
- 14-AR-0200: Research Study for Vasculitis
- 94-AR-0066: Research Study for Lupus
- 04-H-0202: Pentalogy of Cantrell
- 13-CC-0110: Childhood Onset Brain Injury
- 04-DK-0021: Study for Type 1 and Type 2 Diabetes
- 13-H-0059: Study for Asthma
- 09-NR-0088: Prostate Cancer Study
- 12-DK-0154: Digestive Disorders
- 09-DK-0223: Idiopathic Membranous Nephropathy Study
- 03-E-0099: Do you have an autoimmune disease?
- 11-N-0051: Do you suffer from epilepsy?
Opportunities for Healthy Volunteers
- 07-H-0113: Healthy Volunteers Needed
- 16-I-0039: Healthy Volunteers Needed for Future Investigational Malaria Research
- 20-HG-0090: Genetics of COVID-19 Susceptibility and Manifestations
- 19-HG-0092: New Approaches for Empowering Studies of Asthma in Populations of African Descent
- 12-D-0100: Oral Microbial and Immunological Characterization of Patients with Immune Dysfunction
- 15-CC-0164: Effect of Exercise Training on Physical, Cognitive and Behavioral Function in Patients with Traumatic Brain Injury
- 18-DK-0132: Brain Dopamine Function in Human Obesity
- 19-H-0120: Pilot Study for Geospatial Analysis of Neighborhood Environmental Stress in Relation to Biological Markers of Cardiovascular Health and Health Behaviors in Women
- 16-HG-0017: The Genomic Services Research Program
- 11-M-0251: How Does Puberty Affect Brain Development?
- 17-AA-0093: A Pilot Study Exploring Gut-Brain and Brain-Gut Interactions in Alcohol Use Disorder via Microbiota Investigations
- 17-AA-0171: Do You Drink Alcohol?
- 16-H-0144: Impact of Elastin Mediated Vascular Stiffness on End Organs
- 07-N-0122: Modulation of Motor Function by Stimulation of the Central and Peripheral Nervous System
- 19-DK-0072: Non-Alcoholic Fatty Liver Disease, the Hepatic Response to Oral Glucose, and the Effect of Semaglutide (NAFLD HEROES)
- 19-DK-0072: Hígado graso no alcohólico, respuesta hepática a la glucosa oral y efecto de la semaglutida (NAFLD HEROES)
- 16-N-0031: An All-Night Functional Magnetic Resonance Imaging Sleep Study With Auditory Stimuli
- 19-C-0040: Do you have a genetic risk factor for Prostate Cancer?
- 19-I-0031: 18-50 year olds needed for HIV vaccine research
- 16-I-0078: NIAID Microbiome Study Seeks Healthy Volunteers
- 17-AA-0178: Healthy adults needed for brain imaging study (ages 18 to 55)
- 13-CC-0099: Do you have chronic kneecap pain?
- 13-CC-0099: ¿Dolor crónico de rótula?
- 08-AA-0178: Do you drink alcohol?
- 18-H-0146: Genotype -Phenotype Correlation of PKLR Variants with Pyruvate Kinase, 2,3-Diphosphglycerate and ATP Activities in Red Blood Cells of Patients with Sickle Cell Disease
- 13-DK-0200: The Mechanism of Human Non-Shivering Thermogenesis and Basal Metabolic Rate
- 16-AA-0080: Is alcohol affecting your life?
- 15-AA-0186: Newly Developed Functional Magnetic Resonance Imaging (fMRI)
- 17-H-0162: Mobile Health Physical Activity Intervention
- 96-H-0049: Mobilized Leukapharesis Collection for Healthy Volunteers
- 18-I-0105 – VRC 609: Human Monoclonal Antibody
- 17-AA-0093: Brain-Gut connection and alcohol use
- 18-H-0019: Omega-7 Supplement Fish Oil Study
- 13-D-0033: Third Molar Removal and Oral Specimen Acquisition
- 16-AT-0077: Help scientists to understand the brain's response to pain (ages 12 and older)
- 16-N-0058: Help us to better understand chronic fatigue syndrome (ages 18-60)
- 18-DK-0044: 18-50 yo, how do processed foods affect your health?
- 12-DK-0097: (Cohort 4) Caucasian Women, 18-35 Years Old (Inpatient Study)
- 17-AA-0114: 20-65 yo, healthy volunteers for opiate use disorders study
- 14-AA-0144: 18 and older, MRI/PET brain imaging study
- 16-AA-0037: 21-60 yo, drink alcohol?
- 99-H-0076: 18 and older, healthy volunteers for lung inflammation study
- 12-D-0100: 18 and older, healthy volutneers without gum disease
- 15-AA-0127: 21-65 yo, alcohol and early life stress
- 12-HG-0181: 18-55 yo, chromosome study
- 15-H-0017: 18 and older, lung fibrosis
- 15-AT-0132: 18-55 yo, pain study (no MRI)
- 15-AT-0132: 18-55 yo, MRI pain study
- 94-I-0073: 20-40 yo, blood donation for immune diseases study
- 14-AR-0200: Research Study for Vasculitis
- 13-DK-0200: 18-35 yo, men for inpatient metabolism study
- 92-I-0125: 18-59 yo, lymph node biopsy study
- 13-CC-0110: 5 yr and older, movement study
Opportunities for Kids
- 19-CH-0071: An Open-Label Phase 3 Study of the Safety and Efficacy of Pegvisomant in Children with Growth Hormone Excess
- 20-DK-0018: NIDDK Research of Prebiotic Fiber Supplements With Metformin in Youths With Type 2 Diabetes
- 18-CH-0001: Mirror Neuron Network Dysfunction as an Early Biomarker of Neurodevelopmental Disorder
- 18-CC-0052: Near-infrared Spectroscopy and Electroencephalography to Assess Cortical Activation During Motor Tasks in Infants and Toddlers with or at high-risk for Cerebral Palsy and Autism Spectrum Disorder Compared to Infants and Toddlers with Typical Development
- 17-CH-0130: 7-11 year olds needed for NIH "Break it Up" study
- 15-I-0162: Natural History and Genetics of Food Allergy and Related Conditions
- 17-I-0033: Research Participants Needed
- 18-H-0004: Telomere-Related Diseases
- 17-CH-0014: Healthy Girls, 12-17 Year Olds
- 15-CH-0096: Healthy 8-17 Year Olds
- 04-H-0202: Pentalogy of Cantrell
- 03-E-0099: Do you have an autoimmune disease?
- 11-N-0051: Do you suffer from epilepsy?
NIH Centers with Multiple Opportunities for Patients and Healthy Volunteers
- Center for Neuroscience and Regenerative Medicine – Traumatic Brain Injury (TBI) and Post-traumatic Stress Disorder (PTSD)
- Research at the National Institute on Drug Abuse – Teen smokers, smokers, drug users, and comparison groups
To find out more about clinical studies at the NIH Clinical Center or to ask questions about how you or someone you know might participate, call toll free: 1-800-411-1222 (TTY 1-866-411-1010) or e-mail prpl@mail.cc.nih.gov.