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Featured Studies

Office of Patient Recruitment

This web page makes it easy to search for featured research studies at the NIH Clinical Center. You can search for specific studies by entering keywords related to your symptoms in the search box or by using the sort and filter options.


To view a full list of all studies conducted at the NIH Clinical Center, visit Search the Studies.

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42 results
Close-up portrait of a woman with a sorrowful expression, illuminated against a dark background, evoking feelings of loneliness and mental distress

A Feasibility Study of Transcranial Electric Stimulation Therapy (TEST) for Treatment Resistant Depression (TRD)

Dr. Regenold and his team at the National Institutes of Health (NIH) are leading a study to explore an investigational new, non-invasive brain stimulation technique to see if it can safely support people experiencing symptoms of depression.

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If you have questions or would like to learn more about this study, contact 833-JOIN-NIH and refer to study 21-M-0031.
Close-up of a woman looking out a window, reflecting a sense of loneliness

An Investigation of the Antidepressant Effects of (2R,6R)-HNK, an Enhancer of Synaptic Glutamate Release, in Treatment-Resistant Depression

Researchers at the National Institute of Mental Health (NIMH) are studying an investigational drug, HNK, to see if it is effective in treating major depression. If you're 18–70 years old and have major depressive disorder (MDD), you may qualify for this 12- to 14-week inpatient research study.

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If you have questions or would like to learn more about this study, contact 833-JOIN-NIH and refer to study 001602-M.
a group of people smiling

Platelet Volunteers, Longitudinal and Multi-Omic Study

Research Study #002298-H - Researchers at the National Heart, Lung, and Blood Institute are studying how platelets, small pieces of blood cells, work and change over time in healthy people. Your blood donation can help advance medical research and deepen understanding of human health. 

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If you have questions or would like to learn more about this study, contact 833-JOIN-NIH and refer to study 002298-H.
A child sitting in the park listening to music on headphones

Role of GABAergic Transmission in Auditory Processing in Autism Spectrum Disorder

Researchers are studying the brain's response to language and sound. This study uses a repetitive transcranial magnetic stimulation (rTMS), an investigational form of brain stimulation, to measure how different parts of the brain communicate in teens with autism spectrum disorder (ASD). Findings from this study may aid in the development of possible future treatments.

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If you have questions or would like to learn more about this study, contact 833-JOIN-NIH and refer to study 20-M-0159.
a group of women walking to yoga class

NIH Seeking Participants for a Study on Immune Dysfunction in Menopause

Researchers at The National Institutes of Health (NIH) are conducting a study examining inflammation and metabolic dysfunction in menopause. They are looking for both premenopausal and postmenopausal women to participate in the study.

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If you have questions or would like to learn more about this study, contact 866-999-5553 and refer to study 10-H-0126.
Observational Study to Deeply Phenotype Major Organs in Sickle Cell Disease After Curative Therapies

Observational Study to Deeply Phenotype Major Organs in Sickle Cell Disease After Curative Therapies

NIH study # 000479-H investigates the impact of treatments intended to cure sickle cell disease (SCD) on organ function. If you or your loved one has SCD, we invite you to call us to learn more about this observational study.
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If you have questions or would like to learn more about this study, contact 800-411-1222 and refer to study 000479-H.
Role of Genetic Factors in the Development of Lung Disease

Role of Genetic Factors in the Development of Lung Disease

Researchers at the National Institutes of Health (NIH) are studying if low dose CT scans are as effective as regular CT scans to monitor your disease status. Very low-dose scanning uses about 1/30th the amount of radiation as a regular CT scan.
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If you have questions or would like to learn more about this study, contact 800-411-1222 and refer to study 96-H-0100.
Investigation of the Natural Progression of Clonal Hematopoiesis of Indeterminate Potential and Clonal Cytopenia of Undetermined Significance

Investigation of the Natural Progression of Clonal Hematopoiesis of Indeterminate Potential and Clonal Cytopenia of Undetermined Significance

Doctors at the National Institutes of Health (NIH) are conducting a study on patients with Clonal Cytopenia of Uncertain Significance (CCUS). Patients with CCUS have low blood counts and a normal bone marrow exam but more advanced genetic testing shows the presence of a genetic mutation that is likely causing the low counts. The study will look at CCUS and try to determine its relationship to blood cancers and heart disease. The study will also try to discover other new organs or diseases it may be linked with.
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If you have questions or would like to learn more about this study, contact 800-411-1222 and refer to study 19-H-0139.
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