A Phase 1 Study to Evaluate the Safety and Tolerability of Escalating Doses of VAS-101 in Subjects with Stable Sickle Cell Disease
NIH researchers are seeking adults aged 18 and older with sickle cell disease for a research study evaluating VAS-101 gel, an investigational product containing curcumin, to determine whether it is safe and well-tolerated.
NIH Seeking Participants for a Study on Immune Dysfunction in Menopause
Researchers at The National Institutes of Health (NIH) are conducting a study examining inflammation and metabolic dysfunction in menopause. They are looking for both premenopausal and postmenopausal women to participate in the study.
Observational Study to Deeply Phenotype Major Organs in Sickle Cell Disease After Curative Therapies
Role of Genetic Factors in the Development of Lung Disease
Cystic fibrosis (CF) is a progressive, genetic disease that causes persistent lung infections and over time limits the ability of individuals to breathe. Researchers at the National Institutes of Health (NIH) are studying the infection, disease progression, and abnormal genes responsible for cystic fibrosis to better understand the disease process and its effects on breathing.
Role of Genetic Factors in the Development of Lung Disease
Investigation of the Natural Progression of Clonal Hematopoiesis of Indeterminate Potential and Clonal Cytopenia of Undetermined Significance
Investigation of the Natural Progression of Clonal Hematopoiesis of Indeterminate Potential and Clonal Cytopenia of Undetermined Significance
Low-Dose Danazol for the Treatment of Telomere Related Diseases
Researchers at the National Institutes of Health (NIH) are studying if the medication danazol can be used to treat people with short telomere disease who also have bone marrow failure, liver, or lung disease. In recent studies, danazol, at high doses, showed a positive influence on telomere length. Additional research is needed to learn more about the role of different doses of danazol on telomere disease as well as its effects on secondary diseases.