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Featured Studies

Office of Patient Recruitment

This web page makes it easy to search for featured research studies at the NIH Clinical Center. You can search for specific studies by entering keywords related to your symptoms in the search box or by using the sort and filter options.


To view a full list of all studies conducted at the NIH Clinical Center, visit Search the Studies.

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135 results
A diverse group of young adult friends smiling and laughing together while posing for a photo outdoors

EBV gH/gL/gp42-FNP Vaccine

The Epstein-Barr virus (EBV), which causes mono, affects over 90% of the global population and is linked to severe health conditions like cancer and autoimmune diseases. The National Institute of Allergy and Infectious Diseases seeks healthy volunteers aged 18–29 who live in the DMV area to help test a new experimental EBV vaccine.

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Close-up portrait of a woman with a sorrowful expression, illuminated against a dark background, evoking feelings of loneliness and mental distress

A Feasibility Study of Transcranial Electric Stimulation Therapy (TEST) for Treatment Resistant Depression (TRD)

Dr. Regenold and his team at the National Institutes of Health (NIH) are leading a study to explore an investigational new, non-invasive brain stimulation technique to see if it can safely support people experiencing symptoms of depression.

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Three pregnant women sit together, smiling and conversing as they rest their hands on their stomachs

Exploratory Analysis of Factors Contributing to Breast Milk Composition

Dr. Hourigan and her team at the National Institute of Allergy and Infectious Diseases (NIAID) study how pregnancy and breastfeeding shape breast milk's immune, nutritional, and microbiome qualities. While breast milk is known to be the best nutrition for babies, there's still much more to learn. They invite pregnant and breastfeeding women to participate in this research study. You can help! The study design involves multiple visits during pregnancy, lactation, and up to two months after breastfeeding stops. During visits, stool, blood, saliva, and breast milk (if breastfeeding) will be collected, with an option to mail in samples.

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3D medical illustration depicting human kidneys and blood vessels, rendered in a polygonal, interconnected design

A Study of an Investigational Drug for Focal Segmental Glomerulosclerosis (FSGS)

Dr. Gahl and his team at the National Human Genome Research Institute are seeking volunteers aged 18 and older with primary FSGS to participate in a research study on the effects of an experimental drug, ManNAc, on this disease. The study aims to assess the long-term safety and tolerability of ManNAc and determine whether it can reduce protein in the urine of people with FSGS.

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Close-up of a woman looking out a window, reflecting a sense of loneliness

An Investigation of the Antidepressant Effects of (2R,6R)-HNK, an Enhancer of Synaptic Glutamate Release, in Treatment-Resistant Depression

Researchers at the National Institute of Mental Health (NIMH) are studying an investigational drug, HNK, to see if it is effective in treating major depression. If you're 18–70 years old and have major depressive disorder (MDD), you may qualify for this 12- to 14-week inpatient research study.

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a child scratching an allergic reaction

A Biorepository of Multiple Allergic Diseases (MADREP) With Longitudinal Follow-Up

Are allergies holding you back from living life to the fullest? Dr. Paneez Khoury and her team at the National Institute of Allergy and Infectious Diseases seek volunteers aged three and older (parental consent required for minors) with allergies or sinus disease. You don't need a confirmed diagnosis; Individuals with a history of or suspected allergic disease are also welcome.

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Platelet Volunteers, Longitudinal and Multi-Omic Study

Research Study #002298-H - Researchers at the National Heart, Lung, and Blood Institute are studying how platelets, small pieces of blood cells, work and change over time in healthy people. Your blood donation can help advance medical research and deepen understanding of human health. 

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a man and woman smiling while viewing a laptop together

Families SHARE: Virtual Reality Study

Research study #IRB002325 is testing a new virtual tool that helps people learn more about their health and family health history. The goal is to build knowledge, skills, and confidence in talking about health within families.

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A Feasibility Multicenter Phase I Study of Therapeutic Drug Monitoring-Based Atezolizumab Dosing

Researchers are enrolling people with locally advanced or metastatic cancer who are prescribed atezolizumab (alone or with other approved treatments). The study will monitor blood levels to adjust infusion schedules, aiming to see if lower or less frequent doses can be given without reducing effectiveness, over a period of up to 2 years.

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A closeup view showing Helicobacter pylori (H. pylori) bacteria

Be Part of a Study That Could Change How We Detect Helicobacter pylori

This study explores whether the Esophageal String Test (EST), a simple, less invasive procedure can accurately detect H. pylori and antibiotic resistance, compared to traditional testing that uses endoscopic biopsies.

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