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Featured Studies

Office of Patient Recruitment

This web page makes it easy to search for featured research studies at the NIH Clinical Center. You can search for specific studies by entering keywords related to your symptoms in the search box or by using the sort and filter options.


To view a full list of all studies conducted at the NIH Clinical Center, visit Search the Studies.

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57 results
Join the Fight Against Lyme Disease!

Join the Fight Against Lyme Disease!

We are looking for people recently diagnosed with Lyme disease to help us answer important questions about the infection. If you have or had the rash associated with acute Lyme disease (erythema migrans), facial palsy, meningitis, heart block, or arthritis; please consider participating in our study.

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NIH Tests Fecal Transplant in Chronic Granulomatous Disease-Associated Colitis

NIH Tests Fecal Transplant in Chronic Granulomatous Disease-Associated Colitis

Researchers at NIH are testing a new therapy in patients diagnosed with colitis due to chronic granulomatous disease (CGD). The research aims to see if restoring the gut microbiome reduces inflammation in the colon.

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Do you or someone you know want to participate in a clinical research study?

Do you or someone you know want to participate in a clinical research study?

Researchers at the National Institutes of Health (NIH) seek healthy volunteers to provide blood samples for research studies of blood vessels and immune diseases that cause clotting. In this study, investigators want to understand the basis of these diseases to facilitate the development of better treatments.
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Research Study for Severe Aplastic Anemia (SAA)

Research Study for Severe Aplastic Anemia (SAA)

Doctors at the National Institutes of Health (NIH) are conducting a research study to determine the viability and safety of early initiation of oral therapy with cyclosporine and eltrombopag in patients with severe aplastic anemia (SAA).

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Join the Movement to End Malaria! Volunteer for Our Vaccine Study

Join the Movement to End Malaria! Volunteer for Our Vaccine Study

Malaria is a dangerous disease that impacts hundreds of millions of people in Africa, Asia, and Latin America. It can cause severe disease and even death. Researchers at NIH's Laboratory of Malaria Immunology and Vaccinology are seeking healthy volunteers to be part of a malaria vaccine research study.
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Exploring Near Infrared Spectroscopy (NIRS) Technologies for Assessment of Muscle Physiology, Tissue Oxygenation, and Blood Flow in Patients with Sickle Cell Disease (SCD)

Exploring Near Infrared Spectroscopy (NIRS) Technologies for Assessment of Muscle Physiology, Tissue Oxygenation, and Blood Flow in Patients with Sickle Cell Disease (SCD)

Researchers at the National Institutes of Health are investigating the role of Near-Infrared Spectroscopy (NIRS) technologies as a monitoring tool for measuring oxygen levels, blood flow, and the make-up of skin and muscle in patients with sickle cell disease (SCD). In this study, researchers will compare NIRS measurements in people with and without SCD.
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Observational Study of Cardiac Arrhythmias in Subjects Treated with BTK Inhibitors

Observational Study of Cardiac Arrhythmias in Subjects Treated with BTK Inhibitors

Pharmacologic therapy with Bruton's tyrosine kinase (BTK) inhibitors is associated with an increased risk of heart problems like atrial fibrillation, bleeding, and high blood pressure (hypertension) which can lead to sudden death. There is currently no standard for cardiac screening or monitoring patients on BTK inhibitors. Researchers at the National Heart, Lung, and Blood Institute (NHLBI) are investigating the relationship between the development of heart problems in patients on BTKi as it relates to other variables.
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A Phase 1 Randomized, Double-Blind, Placebo-Controlled, Single-Ascending Dose Study to Evaluate the Safety, Tolerability and Pharmacokinetics of Intravenous ZMA001 in Healthy Subjects

A Phase 1 Randomized, Double-Blind, Placebo-Controlled, Single-Ascending Dose Study to Evaluate the Safety, Tolerability and Pharmacokinetics of Intravenous ZMA001 in Healthy Subjects

Healthy volunteers 18-60 years old are needed to test an investigational drug that was developed to reduce blood pressure in the lungs. The PAH team from @NHLBI hope that this investigational study drug may be helpful in treating patients with PAH in the future.
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Natural History Study of CADASIL

Natural History Study of CADASIL

Researchers are examining genetic and physical characteristics of the small vessel disease called CADASIL (cerebral autosomal dominant arteriopathy with subcortical infarct and leukoencephalopathy). They are enrolling volunteers to serve as healthy controls. Compensation is provided.
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