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Vaccine Responses in Patients with B Cell Malignancies

Office of Patient Recruitment

CLL/SLL Malignancy Clinical Trial Investigating Vaccine Effectiveness

a patient receiving a vaccine

Researchers at the National Institutes of Health (NIH) are seeking volunteers with CLL/SLL to participate in a vaccines study with FDA-approved and/or FDA-authorized vaccines. Volunteers will participate in the study for 6 months.

You May Be Eligible for the Study, if You

  • Are at least 18 years old
  • Have a diagnosis of Chronic lymphocytic leukemia (CLL) or small lymphocytic lymphoma (SLL), AND
  • Are currently receiving treatment for your CLL/SLL (e.g. ibrutinib, acalabrutinib or venetoclax)
  • Have not received IVIG (intravenous immunoglobulin) in the past 3 months
  • Have not received anti-CD20 and/or anti-CD19 antibody therapy in the past 6 months
  • Have not previously received an allogeneic stem cell transplant

The NIH Clinical Center, America's Research Hospital located in Bethesda, MD.
Metro red line (Medical Center stop).

For More Information

NIH Clinical Center Office of Patient Recruitment
800-411-1222
TTY users dial 7-1-1
Email: ccopr@nih.gov 
Or go online
Refer to study #000444-H

Department of Health and Human Services
National Institutes of Health Clinical Center (CC)
National Heart, Lung and Blood Institute (NHLBI)