Platelet Volunteers, Longitudinal and Multi-Omic Study
Research Study #002298-H - Researchers at the National Heart, Lung, and Blood Institute are studying how platelets, small pieces of blood cells, work and change over time in healthy people. Your blood donation can help advance medical research and deepen understanding of human health.
A Feasibility Multicenter Phase I Study of Therapeutic Drug Monitoring-Based Atezolizumab Dosing
Researchers are enrolling people with locally advanced or metastatic cancer who are prescribed atezolizumab (alone or with other approved treatments). The study will monitor blood levels to adjust infusion schedules, aiming to see if lower or less frequent doses can be given without reducing effectiveness, over a period of up to 2 years.
NIH Seeking Participants for a Study on Immune Dysfunction in Menopause
Researchers at The National Institutes of Health (NIH) are conducting a study examining inflammation and metabolic dysfunction in menopause. They are looking for both premenopausal and postmenopausal women to participate in the study.
Phase 1 Study with Dose Expansion of the Anti-Mesothelin TNaive/SCM hYP218 (TNhYP218) CAR T Cells in Participants with Mesothelin-Expressing Solid Tumors Including Mesothelioma
Researchers at NCI are developing a new investigational treatment known as TNhYP218 CAR T cells to target and kill tumor cells in people with solid tumors and with those that have high levels of mesothelin (MSLN) including mesothelioma. The study team collects immune cells (T cells); the T cells are genetically modified to target and kill tumor cells to potentially shrink the tumor.
Observational Study to Deeply Phenotype Major Organs in Sickle Cell Disease After Curative Therapies
CAR-T Cell Treatment for Patients with Glypican-3 (GPC3) Positive HCC (A Type of Liver Cancer)
Evaluation for NCI Surgery Branch Clinical Research Protocols
Doctors at the National Cancer Institute (NCI) are looking for volunteers with metastatic cancers, including breast, ovarian, endometrial, gastrointestinal, genitourinary, hepatobiliary, pancreatic, melanoma, non-small cell lung cancer (NSCLC), and multiple myeloma with solid masses. Potential participants will be evaluated with new immunotherapy treatments utilizing cell transfer immunotherapies in a research trial.
Role of Genetic Factors in the Development of Lung Disease