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Featured Studies

This web page makes it easy to search for featured research studies at the NIH Clinical Center. You can search for specific studies by entering keywords related to your symptoms in the search box or by using the sort and filter options.


To view a full list of all studies conducted at the NIH Clinical Center, visit Search the Studies.

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61 results
NIH Clinical Trial for Relapsed/Refractory B-Cell Malignancies

NIH Clinical Trial for Relapsed/Refractory B-Cell Malignancies

Researchers at the National Institutes of Health (NIH) are testing NX-2127, an oral drug that degrades a protein in cancer cells called Bruton's tyrosine kinase (BTK), instead of inhibiting or blocking it like other drugs. NX-2127 may also stimulate your immune T-cells to attack the cancer.
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Surgery as a Treatment for Medically Intractable Epilepsy

Surgery as a Treatment for Medically Intractable Epilepsy

The National Institute of Neurological Disorders and Stroke at the National Institutes of Health Clinical Center is looking for individuals with severe epilepsy or individuals who have experienced persistent seizure activity that cannot be controlled with medication, to participate in this research study. The goal of this research study is to provide surgical treatment to control these types of seizures. Participation requires an inpatient stay of up to 4 weeks, plus 3 outpatient visits within 2 years after surgery.

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Effect of Dietary Omega-7 Palmitoleic Acid-Rich Oil on Lipoprotein Metabolism and Satiety in Adults

Effect of Dietary Omega-7 Palmitoleic Acid-Rich Oil on Lipoprotein Metabolism and Satiety in Adults

Heart disease is the leading cause of death and disability in the United States. Omega-7 fatty acids are found in the oil extracted from certain fish and nuts like macadamia. Palmitoleic acid is one of the most common omega-7 fatty acids. Many studies suggest that this oil is good for heart health. Researchers at the National Institutes of Health (NIH) want to find out more about these potential benefits.
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Rituximab Plus Cyclosporine in Idiopathic Membranous Nephropathy

Rituximab Plus Cyclosporine in Idiopathic Membranous Nephropathy

The National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) is conducting a pilot intervention study for patients diagnosed with idiopathic membranous nephropathy. The purpose of this study is to evaluate the safety and effectiveness of Rituximab plus Cyclosporine in the treatment of membranous nephropathy. There is no cost for study-related medications or tests received.
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Vaccine Responses in Patients with B Cell Malignancies

Vaccine Responses in Patients with B Cell Malignancies

Research Study 000444-H investigating how well the following vaccines work in patients with CLL/SLL malignancies: SHINGRIX and influenza vaccine. If you are currently receiving treatment for your CLL/SLL (e.g. ibrutinib, acalabrutinib or venetoclax), you may be able to participate.
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NIH Research of Multiple Sclerosis and Related Conditions

NIH Research of Multiple Sclerosis and Related Conditions

The National Institutes of Health (NIH) is conducting a research study of the causes and responses to treating multiple sclerosis (MS) and other brain and spine inflammatory conditions. Join this study if you have MS or a related disease. Although the study does not offer treatment options, your participation may help in future discoveries and inspire hope.
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A Study of Anti-Cancer Drug Abemaciclib on Brain Tumors

A Study of Anti-Cancer Drug Abemaciclib on Brain Tumors

Researchers want to see if they can measure the amount of anti-cancer drug, Abemaciclib in a brain tumor and brain fluid after a patient has taken this drug for a few days. These findings can help explain how much drug gets into the brain and how drugs work to shrink high grade gliomas to improve outcomes for these patients.
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Famine from Feast: Linking Vitamin C, Red Blood Cell Fragility, and Diabetes

Famine from Feast: Linking Vitamin C, Red Blood Cell Fragility, and Diabetes

The National Institutes of Health (NIH) researchers are enrolling adult volunteers in a study investigating the role of Vitamin C in red blood cells of patients with type 2 diabetes. Findings may help improve future treatment and care of people with diabetes.
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18F-DCFPyL PET/CT in Hepatocellular Carcinoma

18F-DCFPyL PET/CT in Hepatocellular Carcinoma

Researchers at the National Cancer Institute (NCI) are conducting a clinical trial to study new imaging techniques for those with HCC. Pictures (Images) are taken with a positron emission tomography (PET) using a new investigational imaging radiotracer, 18 F-DCFPyL. Our research study focus is to see if this tracer will improve images taken of your liver to identify HCC tumors earlier in the disease process. We will also determine if we can see differences between treated tumors and the development of new tumors.
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Join the Fight Against Lyme Disease!

Join the Fight Against Lyme Disease!

We are looking for people recently diagnosed with Lyme disease to help us answer important questions about the infection. If you have or had the rash associated with acute Lyme disease (erythema migrans), facial palsy, meningitis, heart block, or arthritis; please consider participating in our study.

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