Skip to main content

Patient Recruitment

Williams Syndrome (WS) and Supravalvular Aortic Stenosis (SVAS)

Elastin (ELN) and Arterial Stiffness

hands of an adult and a child holding a toy heart

human cells

Researchers at the National Institutes of Health (NIH) seek patients with Williams Syndrome (WS) or Supravalvular Aortic Stenosis (SVAS) to join a research study. Researchers want to see how blood vessel elasticity and stiffness affect the heart, gut, kidneys, and the brain in people with Williams Syndrome.

Eligible Participants:

  • Are 3 to 85 years old
  • Have been diagnosed with Williams syndrome or SVAS (ELN gene mutation) by a physician
  • Individuals with WS or children with ELN gene mutations must have parent/guardian for consent

Study participants:

  • Will have their medical records reviewed and receive a physical exam
  • Every year, participants will have imaging tests and measurements of blood vessel function over the course of several days
  • Have the option of yearly study visits for up to 10 years
  • Receive study-related tests provided at no cost
  • May receive compensation and travel assistance

Location: The NIH Clinical Center, America's Research Hospital, is located on the Metro red line (Medical Center) in Bethesda, Maryland.

For more information, contact:
The Office of Patient Recruitment
TTY users call via MD Relay 7-1-1
Se habla español

Or go online:
Refer to study 16-H-0144

Department of Health and Human Services
National Institutes of Health Clinical Center (CC)
National Heart, Lung and Blood Institute (NHLBI)

NOTE: PDF documents require the free Adobe Reader.

This page last updated on 10/22/2021

You are now leaving the NIH Clinical Center website.

This external link is provided for your convenience to offer additional information. The NIH Clinical Center is not responsible for the availability, content or accuracy of this external site.

The NIH Clinical Center does not endorse, authorize or guarantee the sponsors, information, products or services described or offered at this external site. You will be subject to the destination site’s privacy policy if you follow this link.

More information about the NIH Clinical Center Privacy and Disclaimer policy is available at