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Patient Recruitment

Patients Receiving Radiation Therapy for Brain Metastases Needed

Neuropsychological Evaluation for Patients with Brain Metastases

medical illustration of a human brain

In life neuropsychological functions like memory, attention-processing speed, reading and motors skills play an important role when doing daily activities and should be included when determining treatment options. Currently there are no standardized sets of tests to predict changes in neuropsychological functioning in patients treated with radiation for brain metastases. Doctors at the National Institutes of Health (NIH) are conducting a research study evaluating neuropsychological functions in patients treated for brain metastases.


  • Patients receive a 2-week course of radiation therapy to the brain, given daily (5 days a week).
  • Neuropsychological testing to measure cognitive thinking abilities.
  • Questionnaires to assess quality of life and daily living skills.
  • Patients have MRI scans and blood and urine tests.
  • All tests and medical procedures are at no cost to the patient.
  • Travel compensation is provided.


  • Patients 18 years of age or older.
  • Patients who have a pathology confirmed for metastatic disease with brain metastases as identified on brain MRI scan with intravenous contrast.
  • Patient who have primary medical or surgical oncologist in the community who is willing to collaborate in this research study.
  • Patients willing to sign a document of informed consent indicating their understanding of the investigational nature and the risks of this study.
  • If you are female, you must NOT be pregnant or breast feeding.

All tests and medical procedures are at no cost to you. Travel compensation is provided.

The NIH Clinical Center is America's Research Hospital and located in Bethesda, MD (in the Washington, DC metro area).

For more information:
NIH Clinical Center Office of Patient Recruitment
800-411-1222 (refer to NIH study #08-C-0214)
TTY users call via MD Relay 7-1-1
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Or go online:

Department of Health and Human Services
National Institutes of Health Clinical Center (CC)
National Cancer Institute (NCI)

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This page last updated on 10/22/2021

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