25 results

NIH Tests Fecal Transplant in Chronic Granulomatous Disease-Associated Colitis
Researchers at NIH are testing a new therapy in patients diagnosed with colitis due to chronic granulomatous disease (CGD). The research aims to see if restoring the gut microbiome reduces inflammation in the colon.

A Phase 1 Randomized, Double-Blind, Placebo-Controlled, Single-Ascending Dose Study to Evaluate the Safety, Tolerability and Pharmacokinetics of Intravenous ZMA001 in Healthy Subjects
Healthy volunteers 18-60 years old are needed to test an investigational drug that was developed to reduce blood pressure in the lungs. The PAH team from @NHLBI hope that this investigational study drug may be helpful in treating patients with PAH in the future.
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Natural History Study of CADASIL
Researchers are examining genetic and physical characteristics of the small vessel disease called CADASIL (cerebral autosomal dominant arteriopathy with subcortical infarct and leukoencephalopathy). They are enrolling volunteers to serve as healthy controls. Compensation is provided.
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Nicotinamide Riboside and Ketone Metabolism
Dr. Kevin Hall and his team at the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) are seeking male volunteers aged 18-65 and female volunteers aged 18-50 for a study on how low-carb (ketogenic) diets, with or without an investigational dietary supplement called Nicotinamide Riboside, impacts energy levels and metabolism during sleep.
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