26 results
An Open-Label Phase 3 Study of the Safety and Efficacy of Pegvisomant in Children with Growth Hormone Excess
Gigantism is a condition characterized by excessive growth and height significantly above average, caused by over-production of growth hormone (GH) during childhood. Investigators at the National Institutes of Health (NIH) want to see if a drug that antagonizes growth hormone action, called pegvisomant, can help children and adolescents with gigantism.
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An Open-Label, Proof of Concept Study of Vorinostat for the Treatment of Moderate-to-Severe Crohn s Disease and Maintenance Therapy with Ustekinumab
Crohn's disease is a chronic bowel illness that is a lifelong condition characterized by relapsing inflammation. Although there is no cure for Crohn's disease, researchers at the National Institutes of Health (NIH) are investigating if Vorinostat is safe for people with Crohn's Disease. Participants will receive maintenance therapy with Stelara® after successful treatment with Vorinostat.
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Screening of Healthy Volunteers for Investigational Antimalarial Drugs, Malaria Vaccines, and Controlled Human Malaria Challenge
Researchers at National Institutes of Health (NIH) Clinical Center are recruiting healthy adults, ages 18-50, to undergo an initial assessment to determine if they will qualify for future malaria studies. These future studies may involve evaluation of experimental medications, vaccines, and vaccine strategies to prevent malaria.
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Natural History and Genetics of Food Allergy and Related Conditions
The NIH is seeking children ages 2 and older with a history of eczema to participate in a study to identify better ways to diagnose food allergies. Participants do not need to have food allergies. Through this study, we hope to improve the ways food allergies are diagnosed and managed in children with eczema. Participants will not be charged for any service offered, including medications, and medical insurance is not required.
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Children's Growth and Behavior Study
Researchers at the NIH Clinical Center are seeking healthy children for a study of growth and health behaviors. The purpose of the study is to better understand growth in children and adolescents.
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NIH Research of Multiple Sclerosis and Related Conditions
The National Institutes of Health (NIH) is conducting a research study of the causes and responses to treating multiple sclerosis (MS) and other brain and spine inflammatory conditions. Join this study if you have MS or a related disease. Although the study does not offer treatment options, your participation may help in future discoveries and inspire hope.
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