Featured Studies

The National Institutes of Health (NIH) Clinical Center seeks volunteers with type 1 or type 2 diabetes to join a research study. If your diabetes has affected your eyes, kidneys, or other organs you may be interested in participating. Researchers want to learn how the body controls vitamin C levels in those with diabetes.

The National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) is conducting a pilot intervention study for patients diagnosed with idiopathic membranous nephropathy. The purpose of this study is to evaluate the safety and effectiveness of Rituximab plus Cyclosporine in the treatment of membranous nephropathy. There is no cost for study-related medications or tests received.

Thyroid cancer accounts for the vast majority of all types of cancer and little is known about the possible genes that may cause the cancer. An estimated 5% of all thyroid cancers are hereditary. If three or more first-degree relatives are affected, there is a greater than 94% chance that these cases are familial non-medullary thyroid cancer (FNMTC). Researchers at the National Institutes of Health (NIH) are conducting a research study to develop the best ways to evaluate, determine best screening strategy, and identify genes that may indicate vulnerability to FNMTC.

Researchers at the National Cancer Institute (NCI) are conducting a clinical trial to study new imaging techniques for those with HCC. Pictures (Images) are taken with a positron emission tomography (PET) using a new investigational imaging radiotracer, 18 F-DCFPyL. Our research study focus is to see if this tracer will improve images taken of your liver to identify HCC tumors earlier in the disease process. We will also determine if we can see differences between treated tumors and the development of new tumors.

Diets worldwide include both processed and unprocessed foods. Researchers at the National Institutes of Health (NIH) in Bethesda, Maryland seek adult volunteers between 18-60 years old to participate in a study examining how processed and unprocessed foods affect metabolic health. Participants will be required to remain at the NIH Clinical Center for one 4-week stay and eat only the foods provided.

Researchers want to see if they can measure the amount of anti-cancer drug, Abemaciclib in a brain tumor and brain fluid after a patient has taken this drug for a few days. These findings can help explain how much drug gets into the brain and how drugs work to shrink high grade gliomas to improve outcomes for these patients.

Myelodysplastic syndromes (MDS) are disorders caused by abnormal blood cell production, potentially leading to low cell counts and increased susceptibility to clotting and infections. Past research suggests that inflammation may trigger these abnormalities, and this study seeks to further understand and improve treatment strategies for MDS by investigating the role of inflammation in bone marrow cell development.

Dr. Kevin Hall and his team at the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) are seeking male volunteers aged 18-65 and female volunteers aged 18-50 for a study on how low-carb (ketogenic) diets, with or without an investigational dietary supplement called Nicotinamide Riboside, impacts energy levels and metabolism during sleep.

Researchers from the National Cancer Institute at the NIH Clinical Center are currently looking for patients who have HER2-expressing endometrial cancer. The purpose of the study is to test two investigational study drugs, a vaccine that targets HER2 (AdHER2DC) and a drug that is expected to improve immune cell function (N-803). These study drugs will be used with pembrolizumab and lenvatinib which are FDA approved to treat endometrial cancer.

A study at NIH is recruiting healthy African Americans and African-born individuals to better understand diabetes and heart disease risk in Black populations. If you are African American or African-born Black between the ages of 18 and 70 years.