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Featured Studies

Office of Patient Recruitment

This web page makes it easy to search for featured research studies at the NIH Clinical Center. You can search for specific studies by entering keywords related to your symptoms in the search box or by using the sort and filter options.


To view a full list of all studies conducted at the NIH Clinical Center, visit Search the Studies.

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63 results
mosquito biting human skin

Phase 1 Study of Induced Blood-Stage Malaria in Healthy Malaria-Naive Adults to Assess the Safety and Infectivity of Plasmodium Vivax Challenge Agent and Evaluate Transmission in Mosquito Feeding Assays

To learn how malaria develops in people; how the body's immune system reacts to malaria; and how malaria spreads from people to mosquitoes.

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A father checking his child's forehead temperature for a fever

Evaluating the Genetics and Immunology of Periodic Fever, Aphthous Stomatitis, Pharyngitis, and Cervical Adenitis (PFAPA) Syndrome and Other Tonsil Disorders

Do you or your child experience recurring fever with mouth sores (canker sores), sore throat, or swollen neck glands? These could be symptoms of PFAPA, the most common periodic fever syndrome in children.

Dr. Manthiram and her team at the National Institute of Allergy and Infectious Diseases (NIAID) seek volunteers who are one month and older (parental consent required for minors) to participate in a research study to better understand PFAPA. Compensation provided. Participants can join from home anywhere in the USA or internationally.

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Observational Study to Deeply Phenotype Major Organs in Sickle Cell Disease After Curative Therapies

Observational Study to Deeply Phenotype Major Organs in Sickle Cell Disease After Curative Therapies

NIH study # 000479-H investigates the impact of treatments intended to cure sickle cell disease (SCD) on organ function. If you or your loved one has SCD, we invite you to call us to learn more about this observational study.
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Treatment of Patients With Cysticercosis With Praziquantel or Albendazole

Treatment of Patients With Cysticercosis With Praziquantel or Albendazole

Are you from Mexico, Central or South America, or India with hydrocephalus, seizures, or an inflammatory condition of the central nervous system without a diagnosis? The National Institutes of Health (NIH) is studying people with cysticercosis and those likely to have cysticercosis. All study related tests and procedures are provided at no cost to you. Travel to and from NIH may be reimbursed.

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Role of Genetic Factors in the Development of Lung Disease

Role of Genetic Factors in the Development of Lung Disease

Cystic fibrosis (CF) is a progressive, genetic disease that causes persistent lung infections and over time limits the ability of individuals to breathe. Researchers at the National Institutes of Health (NIH) are studying the infection, disease progression, and abnormal genes responsible for cystic fibrosis to better understand the disease process and its effects on breathing.

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Improved Methods of Cell Selection for Bone Marrow Transplant Alternatives

Improved Methods of Cell Selection for Bone Marrow Transplant Alternatives

Investigators at the National Heart, Lung, and Blood Institute are seeking healthy volunteers, 18-60 years old, who are interested in participating in a study to collect mobilized blood stem cells that will be used in the laboratory to develop new treatments for blood diseases.
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Recruitment and Apheresis Collection of Peripheral Blood Hematopoietic Stem Cells, Mononuclear Cells and Granulocytes

Recruitment and Apheresis Collection of Peripheral Blood Hematopoietic Stem Cells, Mononuclear Cells and Granulocytes

Doctors at the National Institutes of Health (NIH) are investigating new techniques needed to develop gene therapy or other treatment for certain inherited immune system diseases. If you have an inherited disease that is affecting your blood or bone marrow cell that generate blood cells, you may be eligible to participate in this research study. Participants will be screened with a medical history, physical examination and blood and urine tests.

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Role of Genetic Factors in the Development of Lung Disease

Role of Genetic Factors in the Development of Lung Disease

Researchers at the National Institutes of Health (NIH) are studying if low dose CT scans are as effective as regular CT scans to monitor your disease status. Very low-dose scanning uses about 1/30th the amount of radiation as a regular CT scan.
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Investigation of the Natural Progression of Clonal Hematopoiesis of Indeterminate Potential and Clonal Cytopenia of Undetermined Significance

Investigation of the Natural Progression of Clonal Hematopoiesis of Indeterminate Potential and Clonal Cytopenia of Undetermined Significance

Doctors at the National Institutes of Health (NIH) are conducting a study on patients with Clonal Cytopenia of Uncertain Significance (CCUS). Patients with CCUS have low blood counts and a normal bone marrow exam but more advanced genetic testing shows the presence of a genetic mutation that is likely causing the low counts. The study will look at CCUS and try to determine its relationship to blood cancers and heart disease. The study will also try to discover other new organs or diseases it may be linked with.
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