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Featured Studies

Office of Patient Recruitment

This web page makes it easy to search for featured research studies at the NIH Clinical Center. You can search for specific studies by entering keywords related to your symptoms in the search box or by using the sort and filter options.


To view a full list of all studies conducted at the NIH Clinical Center, visit Search the Studies.

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57 results
Viral Load in Blood and Lymph Tissues of HIV-Infected Individuals

Viral Load in Blood and Lymph Tissues of HIV-Infected Individuals

Doctors at the National Institutes of Health (NIH) are conducting a research study to learn more about the immune system and its response to HIV infection in lymph nodes. All study-related tests and procedures are provided at no cost to the study participant.
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Role of Genetic Factors in the Development of Lung Disease

Role of Genetic Factors in the Development of Lung Disease

Cystic fibrosis (CF) is a progressive, genetic disease that causes persistent lung infections and over time limits the ability of individuals to breathe. Researchers at the National Institutes of Health (NIH) are studying the infection, disease progression, and abnormal genes responsible for cystic fibrosis to better understand the disease process and its effects on breathing.

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Improved Methods of Cell Selection for Bone Marrow Transplant Alternatives

Improved Methods of Cell Selection for Bone Marrow Transplant Alternatives

Investigators at the National Heart, Lung, and Blood Institute are seeking healthy volunteers, 18-60 years old, who are interested in participating in a study to collect mobilized blood stem cells that will be used in the laboratory to develop new treatments for blood diseases.
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Viral Load in Blood and Lymph Tissues of HIV-Infected Individuals

Viral Load in Blood and Lymph Tissues of HIV-Infected Individuals

Doctors at the National Institutes of Health are conducting a research study (92-I-0125) to learn more about the immune system and how it responds to HIV infection in blood, lymph nodes, and bone marrow. We are seeking healthy volunteers to have a lymph node biopsy to compare with patients who have HIV.
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Role of Genetic Factors in the Development of Lung Disease

Role of Genetic Factors in the Development of Lung Disease

Researchers at the National Institutes of Health (NIH) are studying if low dose CT scans are as effective as regular CT scans to monitor your disease status. Very low-dose scanning uses about 1/30th the amount of radiation as a regular CT scan.
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Investigation of the Natural Progression of Clonal Hematopoiesis of Indeterminate Potential and Clonal Cytopenia of Undetermined Significance

Investigation of the Natural Progression of Clonal Hematopoiesis of Indeterminate Potential and Clonal Cytopenia of Undetermined Significance

Doctors at the National Institutes of Health (NIH) are conducting a study on patients with Clonal Cytopenia of Uncertain Significance (CCUS). Patients with CCUS have low blood counts and a normal bone marrow exam but more advanced genetic testing shows the presence of a genetic mutation that is likely causing the low counts. The study will look at CCUS and try to determine its relationship to blood cancers and heart disease. The study will also try to discover other new organs or diseases it may be linked with.
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Recruitment and Apheresis Collection of Peripheral Blood Hematopoietic Stem Cells, Mononuclear Cells and Granulocytes

Recruitment and Apheresis Collection of Peripheral Blood Hematopoietic Stem Cells, Mononuclear Cells and Granulocytes

The National Institutes of Health seeks healthy volunteers to participate in a research study for the collection of blood components such as platelets and plasma. Doctors are studying new techniques needed to develop gene therapy and other treatments for certain inherited immune system diseases. All participants will be screened with a medical history, physical examination, blood and urine tests.
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Genotype -Phenotype Correlation of PKLR Variants with Pyruvate Kinase, 2,3-Diphosphglycerate and ATP Activities in Red Blood Cells of Patients with Sickle Cell Disease

Genotype -Phenotype Correlation of PKLR Variants with Pyruvate Kinase, 2,3-Diphosphglycerate and ATP Activities in Red Blood Cells of Patients with Sickle Cell Disease

Doctors at the National Institutes of Health (NIH) seek healthy volunteers (with or without a sickle cell trait) and patients with sickle cell for a research study. Sickle cell disease is a genetic blood disorder that occurs mainly in people of African descent. Study participants will have a one-time visit to the NIH to provide blood samples. Researchers hope this study will help us better understand sickle cell disease.
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Low-Dose Danazol for the Treatment of Telomere Related Diseases

Low-Dose Danazol for the Treatment of Telomere Related Diseases

Researchers at the National Institutes of Health (NIH) are studying if the medication danazol can be used to treat people with short telomere disease who also have bone marrow failure, liver, or lung disease. In recent studies, danazol, at high doses, showed a positive influence on telomere length. Additional research is needed to learn more about the role of different doses of danazol on telomere disease as well as its effects on secondary diseases.

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Early Clonal Dynamics During Venetoclax Treatment for Chronic Lymphocytic Leukemia (CLL)

Early Clonal Dynamics During Venetoclax Treatment for Chronic Lymphocytic Leukemia (CLL)

The research study sets out to learn about changes in the genetic makeup of CLL during the early phase of treatment with venetoclax. The initial phase of venetoclax therapy can be medically and logistically challenging. Patients will receive expert medical care at the National Institutes of Health (NIH).
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