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Featured Studies

Office of Patient Recruitment

This web page makes it easy to search for featured research studies at the NIH Clinical Center. You can search for specific studies by entering keywords related to your symptoms in the search box or by using the sort and filter options.


To view a full list of all studies conducted at the NIH Clinical Center, visit Search the Studies.

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13 results
A closeup view showing Helicobacter pylori (H. pylori) bacteria

Be Part of a Study That Could Change How We Detect Helicobacter pylori

This study explores whether the Esophageal String Test (EST), a simple, less invasive procedure can accurately detect H. pylori and antibiotic resistance, compared to traditional testing that uses endoscopic biopsies.

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A doctor examining a patient's throat

An Open-Label Study of Zemaira (Alpha 1-Trypsin Inhibitor) in Subjects with Eosinophilic Esophagitis

Research Study #001854-I to explore the effects of Zemaira® for individuals with eosinophilic esophagitis (EoE). This study aims to understand how people with EoE feel while taking Zemaira® and whether it provides any benefits. By joining this research, you'll have the opportunity to contribute to medical advancements that could improve care for those with EoE. Every patient plays a key role in shaping future treatments and expanding knowledge about this condition. 

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A father checking his child's forehead temperature for a fever

Evaluating the Genetics and Immunology of Periodic Fever, Aphthous Stomatitis, Pharyngitis, and Cervical Adenitis (PFAPA) Syndrome and Other Tonsil Disorders

Do you or your child experience recurring fever with mouth sores (canker sores), sore throat, or swollen neck glands? These could be symptoms of PFAPA, the most common periodic fever syndrome in children.

Dr. Manthiram and her team at the National Institute of Allergy and Infectious Diseases (NIAID) seek volunteers who are one month and older (parental consent required for minors) to participate in a research study to better understand PFAPA. Compensation provided. Participants can join from home anywhere in the USA or internationally.

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Treatment of Patients With Cysticercosis With Praziquantel or Albendazole

Treatment of Patients With Cysticercosis With Praziquantel or Albendazole

Are you from Mexico, Central or South America, or India with hydrocephalus, seizures, or an inflammatory condition of the central nervous system without a diagnosis? The National Institutes of Health (NIH) is studying people with cysticercosis and those likely to have cysticercosis. All study related tests and procedures are provided at no cost to you. Travel to and from NIH may be reimbursed.

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Viral Load in Blood and Lymph Tissues of HIV-Infected Individuals

Viral Load in Blood and Lymph Tissues of HIV-Infected Individuals

Doctors at the National Institutes of Health (NIH) are conducting a research study to learn more about the immune system and its response to HIV infection in lymph nodes. All study-related tests and procedures are provided at no cost to the study participant.
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An Open-Label, Proof of Concept Study of Vorinostat for the Treatment of Moderate-to-Severe Crohn s Disease and Maintenance Therapy with Ustekinumab

An Open-Label, Proof of Concept Study of Vorinostat for the Treatment of Moderate-to-Severe Crohn s Disease and Maintenance Therapy with Ustekinumab

Crohn's disease is a chronic bowel illness that is a lifelong condition characterized by relapsing inflammation. Although there is no cure for Crohn's disease, researchers at the National Institutes of Health (NIH) are investigating if Vorinostat is safe for people with Crohn's Disease. Participants will receive maintenance therapy with Stelara® after successful treatment with Vorinostat.
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Spironolactone for Pulmonary Arterial Hypertension

Spironolactone for Pulmonary Arterial Hypertension

Researchers at the National Institutes of Health (NIH) Clinical Center are testing if spironolactone can be used to treat PAH. Spironolactone is a medication that can help with fluid retention, however it may also be beneficial to adults with PAH by controlling inflammation and improving blood vessel function in the lungs.
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COVID-19, Chronic Adaptation and Response to Exercise (COVID-CARE): A Randomized Controlled Trial
COVID-19 Adaptation and Response to Exercise

COVID-19, Chronic Adaptation and Response to Exercise (COVID-CARE): A Randomized Controlled Trial COVID-19 Adaptation and Response to Exercise (En español)

Researchers at the National Institutes of Health's (NIH) Clinical Center are looking for adult volunteers for a study on whether an aerobic exercise program benefits survivors of COVID-19. (En español)
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Famine from Feast: Linking Vitamin C, Red Blood Cell Fragility, and Diabetes

Famine from Feast: Linking Vitamin C, Red Blood Cell Fragility, and Diabetes

The National Institutes of Health (NIH) researchers are enrolling adult volunteers in a study investigating the role of Vitamin C in red blood cells of patients with type 2 diabetes. Findings may help improve future treatment and care of people with diabetes.
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NIH Research of Multiple Sclerosis and Related Conditions

NIH Research of Multiple Sclerosis and Related Conditions

The National Institutes of Health (NIH) is conducting a research study of the causes and responses to treating multiple sclerosis (MS) and other brain and spine inflammatory conditions. Join this study if you have MS or a related disease. Although the study does not offer treatment options, your participation may help in future discoveries and inspire hope.
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