Clinical and Genetic Studies in Familial Non-medullary Thyroid Cancer
Thyroid cancer accounts for the vast majority of all types of cancer and little is known about the possible genes that may cause the cancer. An estimated 5% of all thyroid cancers are hereditary. If three or more first-degree relatives are affected, there is a greater than 94% chance that these cases are familial non-medullary thyroid cancer (FNMTC). Researchers at the National Institutes of Health (NIH) are conducting a research study to develop the best ways to evaluate, determine best screening strategy, and identify genes that may indicate vulnerability to FNMTC.
Clinical Evaluation of Pediatric and Adults with Myelodysplastic Syndromes (MDS)
Myelodysplastic syndromes (MDS) are disorders caused by abnormal blood cell production, potentially leading to low cell counts and increased susceptibility to clotting and infections. Past research suggests that inflammation may trigger these abnormalities, and this study seeks to further understand and improve treatment strategies for MDS by investigating the role of inflammation in bone marrow cell development.