Seeking Adults and Children With MDS or MDS/MPN
Dr. El Jurdi and her team at the National Institutes of Health (NIH) are seeking adults and children aged 12 and older with myelodysplastic syndrome (MDS) or myelodysplastic/myeloproliferative neoplasm (MDS/MPN) for a clinical research study. This clinical research study is evaluating the safety and effectiveness of an investigational drug, pacritinib. Parental consent is required for minors.
A Randomized, Double-Blind, Placebo-Controlled, Flexible Dose Phase 2 Study of Efficacy and Safety of Tirzepatide in Individuals with Alcohol Use Disorder and Metabolic Alcohol-associated Liver Disease
The National Institutes of Health (NIH) is conducting a research study to explore whether an investigational GLP1 medication called Tirzepatide can help people improve liver health. This study focuses on individuals who are overweight and drink alcohol regularly.
Imaging and Biopsy of People with HIV-1 Undergoing Analytic Treatment Interruption
The National Institutes of Health is enrolling adults living with HIV who are on stable antiretroviral therapy (ART) for a clinical research study led by Chuen-Yen Lau, M.D.
Quantifying Associations of Stress and Inflammation-Associated Oral Biomarkers with Oral Health, Oral Health Behaviors, Systemic Biomarkers and Clinical Phenotype in Individuals with Alcohol Use Disorder (AUD)
Poor oral health may increase the risk of serious conditions like diabetes and stroke. Researchers at the National Institutes of Health (NIH) are conducting a study to test a new questionnaire about oral health habits and to learn how oral health behaviors affect inflammation.
A Phase 1 Study to Evaluate the Safety and Tolerability of Escalating Doses of VAS-101 in Subjects with Stable Sickle Cell Disease
NIH researchers are seeking adults aged 18 and older with sickle cell disease for a research study evaluating VAS-101 gel, an investigational product containing curcumin, to determine whether it is safe and well-tolerated.
Safety of Tofacitinib, an Oral Janus Kinase Inhibitor, in Primary Sjögren's Disease Phase IIa Open-Label Clinical Trial and Associated Mechanistic Studies
Dr. Blake Warner and a group of NIH researchers are testing tofacitinib, an investigational oral medication, to help better understand and treat Sjögren's symptoms. Tofacitinib is already approved by the United States Food and Drug Administration (FDA) for other autoimmune conditions and is being used investigationally in this research study.
Observational Study of Dietary Intake and Dietary Behaviors in Adults with Sickle Cell Disease
Are you living with sickle cell disease (SCD)? You may wonder how diet and nutrition affect your overall health and well-being. Researchers at the National Institutes of Health (NIH) are conducting a study to investigate how diet and nutrition impact the physical and mental health of adults with SCD.
VRC 329: A Phase I Open-Label, Clinical Trial To Evaluate the Safety, Tolerability, and Immunogenicity of a Quadrivalent Influenza HA Stem Vaccine VRC-FLUMOS0122-00-VP (STEMos1) With and Without ALFQ Adjuvant in Healthy Adults
Researchers at the NIH Clinical Center are conducting a research study for an investigational vaccine that targets influenza (flu).
Oral Microbial and Immunological Characterization of Patients with Immune Dysfunction
Gum disease (periodontal disease) is being studied at the NIH Clinical Center. Researchers want to learn how a person's immune system affects the health of the mouth. If you have gum disease and want to learn how you can participate contact us.
EBV gH/gL/gp42-FNP Vaccine
The Epstein-Barr virus (EBV), which causes mono, affects over 90% of the global population and is linked to severe health conditions like cancer and autoimmune diseases. The National Institute of Allergy and Infectious Diseases seeks healthy volunteers aged 18–29 who live in the DMV area to help test a new experimental EBV vaccine.