Featured Studies

Do you... Find yourself constantly checking things? Spend lots of time ordering your belongings? Have unusual rituals or habits that seem unnecessary? Do you blurt out comments at inappropriate times, interrupt conversations or speak out of turn or feel you are overly impulsive? The National Human Genome Research Institute (NHGRI) is conducting an outpatient research study on the links between compulsivity, impulsivity and the developing brain in children and young adults.

Pharmacologic therapy with Bruton's tyrosine kinase (BTK) inhibitors is associated with an increased risk of heart problems like atrial fibrillation, bleeding, and high blood pressure (hypertension) which can lead to sudden death. There is currently no standard for cardiac screening or monitoring patients on BTK inhibitors. Researchers at the National Heart, Lung, and Blood Institute (NHLBI) are investigating the relationship between the development of heart problems in patients on BTKi as it relates to other variables.

The research study aims to enhance the understanding of SCD and its associated complications by investigating the relationship between the disease and specific variations of certain genes. If you have SCD, your participation in this study is highly valuable. By participating, you will undergo an evaluation and receive recommendations from a team experienced in the treatment and management of SCD.

A study at NIH is recruiting healthy African Americans and African-born individuals to better understand diabetes and heart disease risk in Black populations. If you are African American or African-born Black between the ages of 18 and 70 years.

The risk of heart disease among African Americans is still common despite a greater understanding of the disease and better approaches to managing it. Healthy cooking and eating patterns can help reduce the risk of heart disease. But things like access to grocery stores and knowledge of good nutrition can affect these healthy patterns. Researchers at The National Institutes of Health want to see if community-based programs can help.

Doctors at the National Institute on Deafness and Other Communication Disorders (NIDCD) are investigating the effectiveness of atorvastatin (a drug used to lower “bad“ cholesterol and fats such as LDL, and triglycerides, and raise “good“ cholesterol such as HDL, in the blood) at reducing the incidence of hearing loss in patients treated with cisplatin for head and neck cancer.

Systemic lupus erythematosus (SLE) creates an imbalance in the innate immune system responsible for chronic inflammation. A study at NHLBI is looking into a Vitamin B supplement, nicotinamide riboside (NR), to see if it improves immune system function in people with SLE. People with SLE will be asked to take the supplement or placebo for 12 weeks. Healthy control subjects will be enrolled to compare baseline blood results but will not take the supplement.

Researchers from the National Cancer Institute at the NIH Clinical Center are currently looking for patients who have HER2-expressing endometrial cancer. The purpose of the study is to test two investigational study drugs, a vaccine that targets HER2 (AdHER2DC) and a drug that is expected to improve immune cell function (N-803). These study drugs will be used with pembrolizumab and lenvatinib which are FDA approved to treat endometrial cancer.