Featured Studies

Researchers at NIH are testing a new therapy in patients diagnosed with colitis due to chronic granulomatous disease (CGD). The research aims to see if restoring the gut microbiome reduces inflammation in the colon.

Each year, the number of cases of tick-borne diseases increases. Researchers at the National Institutes of Health (NIH) Lyme Disease Studies Unit is looking for healthy volunteers to participate in a research study to learn more about how the human immune system responds to tick bites.

Myelodysplastic syndromes (MDS) are disorders caused by abnormal blood cell production, potentially leading to low cell counts and increased susceptibility to clotting and infections. Past research suggests that inflammation may trigger these abnormalities, and this study seeks to further understand and improve treatment strategies for MDS by investigating the role of inflammation in bone marrow cell development.

People with systemic lupus erythematosus (SLE) are at risk of developing complications in their blood vessels. The risks increase for heart attacks or stroke. No medications have been effective at reducing this risk in people with lupus. Researchers at NIH are testing whether a drug (anifrolumab) can improve blood vessel function and reduce blood vessel inflammation in people with (SLE). Participants do not pay for tests, treatments, or procedures.

Healthy volunteers 18-60 years old are needed to test an investigational drug that was developed to reduce blood pressure in the lungs. The PAH team from @NHLBI hope that this investigational study drug may be helpful in treating patients with PAH in the future.

Do you... Find yourself constantly checking things? Spend lots of time ordering your belongings? Have unusual rituals or habits that seem unnecessary? Do you blurt out comments at inappropriate times, interrupt conversations or speak out of turn or feel you are overly impulsive? The National Human Genome Research Institute (NHGRI) is conducting an outpatient research study on the links between compulsivity, impulsivity and the developing brain in children and young adults.

Pharmacologic therapy with Bruton's tyrosine kinase (BTK) inhibitors is associated with an increased risk of heart problems like atrial fibrillation, bleeding, and high blood pressure (hypertension) which can lead to sudden death. There is currently no standard for cardiac screening or monitoring patients on BTK inhibitors. Researchers at the National Heart, Lung, and Blood Institute (NHLBI) are investigating the relationship between the development of heart problems in patients on BTKi as it relates to other variables.

Researchers are examining genetic and physical characteristics of the small vessel disease called CADASIL (cerebral autosomal dominant arteriopathy with subcortical infarct and leukoencephalopathy). They are enrolling volunteers to serve as healthy controls. Compensation is provided.