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Dr. Parizad Torabi-Parizi is interested in understanding mechanisms of lung injury secondary to pulmonary infections by elucidating the nature and extent of the host's immune response.
Dr. Torabi-Parizi earned her undergraduate degree and degree in Medicine from Emory University. She completed her internship and residency training in Internal Medicine at the Johns Hopkins Hospital Osler Training Program.
Dr. Torabi-Parizi completed her fellowship training in Critical Care Medicine at the NIH and was subsequently appointed as Staff Clinician in the Critical Care Medicine Department at the NIH in 2011. She became an Assistant Clinical Investigator in the Critical Care Medicine Department in 2013 and is now a Tenure-Track Investigator. She also chairs the Clinical Center CPR committee.
She has had a long-standing interest in innate immune cell and effector T cell behavior in peripheral tissues, mechanisms regulating this behavior, and possible interventions that might modulate effector responses to improve host outcomes, in the context of critical illness.
See her Intramural Research Program bio page.
Curran C.S., Bolig T., Torabi-Parizi P. Mechanisms and targeted therapies for Pseudomonas aeruginosa lung infection. American Journal of Respiratory and Critical Care Medicine. 2017 Oct 31. doi: 10.1164/rccm.201705-1043SO
Torabi-Parizi P. Critical care management of two patients with Ebola: a biocontainment unit demystified. Critical Care Medicine. 2015 Jun; 43(6):1326-1327.
Torabi-Parizi P., Davey R.T., Suffredini A.F., and Chertow D.S. Ethical and practical considerations in providing critical care to patients with Ebola virus disease. Chest. 2015 Mar 12. doi: 10.1378/chest.15-0278. [Epub ahead of print]
Gerner M.G., Torabi-Parizi P., and Germain R.N. Strategically localized dendritic cells promote rapid T cell responses to lymph-borne vaccines and pathogens. Immunity. 2015 Jan 20; 42(1):172-185.
Subramanian N., Torabi-Parizi P., Gottschalk R., Germain R.N., and Dutta B. Network representations of immune system complexity. Wiley Interdisciplinary Review Systems Biology Medicine. 2015 Jan 27. doi: 10.1002/wsbm.1288 [Epub ahead of print].
Mandl J.N.*, Torabi-Parizi P.*, and Germain R.N. Visualization and Dynamic Analysis of Host-Pathogen Interactions. Current Opinion in Immunology. 2014 Apr 2;29C:8-15.
*Equal 1st author contribution.
Honda T., Egen J.G., Lämmermann T., Kastenmüller W., Torabi-Parizi P., and Germain R.N. Tuning of antigen sensitivity by TCR-dependent negative feedback controls T cell effector function in inflamed tissues. Immunity. 2014 Feb 20;40(2):235-47.
Torabi-Parizi P., Vrisekoop N., et al, and Germain R.N. Pathogen-related differences in the abundance of presented antigen dictate CD4+ T cell dynamic behavior and effector function in the lung. Journal of Immunology. 2014 Feb 15;192(4):1651-60
Kastenmüller W.*, Torabi-Parizi P.*, Subramanian N., Lämmermann T., and Germain R.N. A spatially-organized multicellular innate immune response in lymph nodes limits systemic pathogen spread. Cell; 2012 Sep 14; 150(6): 1235-48.
*Equal 1st author contribution.
Ombrello M.J., Remmers E.F., Sun G., Freeman A.F., Datta S., Torabi-Parizi P., et al. Cold Urticaria, Immunodeficiency, and Autoimmunity Related to PLCG2 Deletions. New England Journal of Medicine; 2012 Jan 26; 366(4): 330-8.
- Clinical Center CEO Award, 2018
- Clinical Center CEO Award, 2017
- Clinical Center Director's Award, 2015
- NIH Director's Award, 2015
- Clinical Center Director's Award, 2014
- NIH Director's Award, 2012
- NIAID Merit Award, 2011
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This page last updated on 09/17/2020