Huan
Mo, MD, MS
Assistant Research Physician
Staff Hematopathologist
Laboratory Medicine
Director, Cohort Analytics Core, NHGRI
Dr. Huan Mo is a Staff Hematopathologist in the Department of Laboratory Medicine at the NIH Clinical Center. Dr. Mo specializes in the diagnostic evaluation of blood and bone marrow disorders.
MD, Sun Yat-sen University, Guangzhou, China
MS, Virginia Commonwealth University
Dr. Huan Mo went to medical school at Sun Yat-sen University, China, completed an anatomic and clinical pathology (AP/CP) residency at Loma Linda University Health (2016-2020) and a clinical fellowship in hematopathology at University of Texas MD Anderson Cancer Center (2021). Dr. Mo is board certified in Anatomic and Clinical Pathology, as well as Hematopathology. Dr. Mo also received a master’s degree in bioinformatics at Virginia Commonwealth University.
From 2012 to 2016, Dr. Mo worked for the Department of Biomedical Informatics at Vanderbilt University Medical Center in electronic health record (EHR)-phenotyping.
In 2022, Dr. Mo joined the Precision Health Informatics Section, NHGRI and direct the newly-founded the Cohort Analytics Core (CAC). In 2023, Dr. Mo joined the Department of Laboratory Medicine (DLM) at the Clinical Center.
- Top downloaded article during its first 12 months of publication in Cytometry Part B: Clinical Cytometry; 2024
- Reviewer Award for the American Medical Informatics Association (AMIA) Informatics Summit; 2024
- College of American Pathologists Annual Meeting Top Five Junior Member Abstract Program Award Winners (Second Place). Orlando, FL; 2019
- Distinguished Clinical Research Informatics Paper Award. American Medical Informatics Association (AMIA). San Francisco, CA, 2015
Mo H, Braylan RC. Myeloma with BRAF p.V600E mutation and atypical plasma cells. EJHaem. 2025 Jan 10;6(1):e1079. PMC11756980.
Tran TC, Schlueter DJ, Zeng C, Mo H, Carroll RJ, Denny JC. PheWAS analysis on large-scale biobank data with PheTK. Bioinformatics. 2024 Dec 26;41(1):btae719. PMC11709244.
Mo H, Channa Y, Ferrara TM, Waxse BJ, Schlueter DJ, Tran TC, Awan AH, Goleva SB, Williams A, Babbar A, Stubblefield O, Keaton JM, Larson EA, Wilke RA, Denny JC. Hyponatremia Associated with the Use of Common Antidepressants in the All of Us Research Program. Clin Pharmacol Ther. 2025 Feb;117(2):534-543. PMC11739749.
Schlueter DJ, Sulieman L, Mo H, Keaton JM, Ferrara TM, Williams A, Qian J, Stubblefield O, Zeng C, Tran TC, Bastarache L, Dai J, Babbar A, Ramirez A, Goleva SB, Denny JC. Systematic replication of smoking disease associations using survey responses and EHR data in the All of Us Research Program. J Am Med Inform Assoc. 2023 Dec 22;31(1):139-153. PMC10746325.
Khanlari M, Mo H, Kim DH, Sakhdari A, Young KH, Jain P, Wang M, Li S, Kanagal-Shamanna R, Miranda RN, Vega F, Medeiros LJ, Ok CY. Blastoid and Pleomorphic Mantle Cell Lymphoma Demonstrate Distinct Clinicopathologic and Genetic Features. Am J Surg Pathol. 2023 Aug 1;47(8):849-858. PMC10348620.
Mo H, Magaki S, Deisch JK, Raghavan R. Isocitrate Dehydrogenase Mutations Are Associated with Different Expression and DNA Methylation Patterns of OLIG2 in Adult Gliomas. J Neuropathol Exp Neurol. 2022 Aug 16;81(9):707-716. PMC9614687.
Bazinet A, Wang A, Li X, Jia F, Mo H, Wang W, Wang SA. Automated quantification of measurable residual disease in chronic lymphocytic leukemia using an artificial intelligence-assisted workflow. Cytometry B Clin Cytom. 2024 Jul;106(4):264-271. PMID: 36824056.
Fang H, Wang SA, Hu S, Konoplev SN, Mo H, Liu W, Zuo Z, Xu J, Jorgensen JL, Yin CC, El Hussein S, Jelloul FZ, Tang Z, Medeiros LJ, Wang W. Acute promyelocytic leukemia: Immunophenotype and differential diagnosis by flow cytometry. Cytometry B Clin Cytom. 2022 Jul;102(4):283-291. PMID: 35716019.
Mo H, Denny JC. The U.S. National Library of Medicine's impact on precision and genomic medicine. Inf Serv Use. 2022 May 10;42(1):71-80. PMC9108560.
Martinez-Baquero D, Sakhdari A, Mo H, Kim DH, Kanagal-Shamanna R, Li S, Young KH, O'Malley DP, Dogan A, Jain P, Wang ML, McDonnell TJ, Miranda RN, Vega F, Medeiros LJ, Ok CY. EZH2 expression is associated with inferior overall survival in mantle cell lymphoma. Mod Pathol. 2021 Dec;34(12):2183-2191. PMC10563799.
Martinez-Baquero D, Sakhdari A, Mo H, Kim DH, Kanagal-Shamanna R, Li S, Young KH, O'Malley DP, Dogan A, Jain P, Wang ML, McDonnell TJ, Miranda RN, Vega F, Medeiros LJ, Ok CY. EZH2 expression is associated with inferior overall survival in mantle cell lymphoma. Mod Pathol. 2021 Dec;34(12):2183-2191. PMC10563799.
Jeong ISD, Mo H, Nguyen A, Chong EG, Tsai HHC, Moyers J, Kim M, Lacy C, Shah V, Lau E, Xu Y, Cao H. Primary chemoradiation with cisplatin versus cetuximab for locally advanced head and neck cancer: a retrospective cohort study. Exp Hematol Oncol. 2020 Aug 5;9:19. PMC7409407.
Mo H, Yau D, Mirshahidi H, Guadiz T, Zuppan CW, Magaki S. AA amyloidosis associated with pulmonary squamous cell carcinoma treated with chemoradiation and immune checkpoint inhibitor therapy. Pathol Int. 2020 May;70(5):303-305. PMID: 32118332.
Doss J, Mo H, Carroll RJ, Crofford LJ, Denny JC. Phenome-Wide Association Study of Rheumatoid Arthritis Subgroups Identifies Association Between Seronegative Disease and Fibromyalgia. Arthritis Rheumatol. 2017 Feb;69(2):291-300. PMC5274573.
Mo H, Thompson WK, Rasmussen LV, Pacheco JA, Jiang G, Kiefer R, Zhu Q, Xu J, Montague E, Carrell DS, Lingren T, Mentch FD, Ni Y, Wehbe FH, Peissig PL, Tromp G, Larson EB, Chute CG, Pathak J, Denny JC, Speltz P, Kho AN, Jarvik GP, Bejan CA, Williams MS, Borthwick K, Kitchner TE, Roden DM, Harris PA. Desiderata for computable representations of electronic health records-driven phenotype algorithms. J Am Med Inform Assoc. 2015 Nov;22(6):1220-30. PMC4639716.
Guo JU, Ma DK, Mo H, Ball MP, Jang MH, Bonaguidi MA, Balazer JA, Eaves HL, Xie B, Ford E, Zhang K, Ming GL, Gao Y, Song H. Neuronal activity modifies the DNA methylation landscape in the adult brain. Nat Neurosci. 2011 Aug 28;14(10):1345-51. PMC3183401.