Department of Perioperative Medicine

DPM Research Program

Diana King, Dr. Michael Iadarola and Dr. Ellen Staedtler in front of presentation

Publications


Dr. Mannes

Andrew J Mannes, MD, ME, MBA
Chief, Perioperative Medicine

Selected Publications

Pritchard WF, Karanian JW, Jung C, Bakhutashvili I, Reed SL, Froelke BR, Barnes T, Stevenson D, Strasser W, Mendosa A, Eckstein D, Wood BJ, Walsh BK, Mannes AJ. Miniature 3D printed pressure-cycled ventilator maintains respiratory homeostasis in swine with induced acute pulmonary injury. (Science Translational Medicine, 2022).

Miao N, Lu X, Orfgen S, Mannes AJ. Intercostal nerve cryoablation: An alternate method for pain management during thoracotomy-A case report. (Translational Periop and Pain Med 2022).

Iadarola MJ, Mannes AJ. Be in it for the long haul: a commentary on human tissue recovery initiatives. (J Pain, 2022).

Kim JJ, Sapio MR, Vazquez FA, Dragan M, Loydpierson A, Zarate C, Iadarola MJ, Mannes AJ. Ketamine. Transcriptional activation, deactivation and rebound patterns in cortex, hippocampus and amygdala in response to ketamine infusion (Frontiers in Molecular Neuroscience, 2022)

Iadarola MJ, Nahama A, Brown DC, Mannes AJ. Pain treatment in canine companion model Î to validate early-stage results and incentivize transition to Human Clinical Trials. (Frontiers in Pharmacology, 2021)

Visit PubMed.gov for a full list of Dr. Mannes's publications.


Dr. Mannes

Michael J. Iadarola, PhD
Senior Research Scientist

Selected Publications

Iadarola MJ, Mannes AJ. Be in it for the long haul: a commentary on human tissue recovery initiatives. (J Pain, 2022).

Kim JJ, Sapio MR, Vazquez FA, Dragan M, Loydpierson A, Zarate C, Iadarola MJ, Mannes AJ. Ketamine. Transcriptional activation, deactivation and rebound patterns in cortex, hippocampus and amygdala in response to ketamine infusion (Frontiers in Molecular Neuroscience, 2022)

Iadarola MJ, Nahama A, Brown DC, Mannes AJ. Pain treatment in canine companion model Î to validate early-stage results and incentivize transition to Human Clinical Trials. (Frontiers in Pharmacology, 2021)

Visit PubMed.gov for a full list of Dr. Iadarola's publications.


Dr. Matthew R. Sapio, PhD

Matthew R. Sapio, PhD
Research Scientist

Selected Publications

Ma W*, Sapio MR*, Manalo AP, Maric D, Dougherty MK, Goto T, Mannes AJ, Iadarola MJ, 2022. Anatomical Analysis of Transient Potential Vanilloid Receptor 1 (Trpv1+) and Mu-Opioid Receptor (Oprm1+) Co-expression in Rat Dorsal Root Ganglion Neurons. Front Mol Neurosci 15, 926596.

Kim JJ*, Sapio MR*, Vazquez FA, Maric D, Loydpierson AJ, Ma W, Zarate CA Jr, Iadarola MJ, Mannes AJ, 2022. Transcriptional Activation, Deactivation and Rebound Patterns in Cortex, Hippocampus and Amygdala in Response to Ketamine Infusion in Rats. Front Mol Neurosci 15, 892345.

Sapio MR, Kim JJ, Loydpierson AJ, Maric D, Goto T, Vazquez FA, Dougherty MK, Narasimhan R, Muhly WT, Iadarola MJ, Mannes AJ, 2021. The Persistent Pain Transcriptome: Identification of Cells and Molecules Activated by Hyperalgesia. J Pain 22, 1146-1179.

Sapio MR, Iadarola MJ, LaPaglia DM, Lehky T, Thurm AE, Danley KM, Fuhr SR, Lee MD, Huey AE, Sharp SJ, Tsao JW, Yanovski JA, Mannes AJ, Han JC, 2019. Haploinsufficiency of the brain-derived neurotrophic factor gene is associated with reduced pain sensitivity. Pain 160, 1070-1081.

Sapio MR, Neubert JK, LaPaglia DM, Maric D, Keller JM, Raithel SJ, Rohrs EL, Anderson EM, Butman JA, Caudle RM, Brown DC, Heiss JD, Mannes AJ, Iadarola MJ, 2018. Pain control through selective chemo-axotomy of centrally projecting TRPV1+ sensory neurons. J Clin Invest 128, 1657-1670.

Visit PubMed.gov for a full list of Dr. Sapio's publications.


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