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Patient Recruitment

Are You Between Age 18–40 Diagnosed With Polycystic Ovarian Syndrome?

a group of women smiling

Women diagnosed with polycystic ovary syndrome (PCOS) needed for a research study at the National Institutes of Health (NIH). Researchers want to learn more about how a medication may be used to help your body's insulin work better and if this can improve your overall metabolic health.

During the study you will:

  • Have a medical history and physical exam
  • Have 4 outpatient visits to include blood tests, EKG, and questionnaires
  • Have 4 separate inpatient visits at the NIH Clinical Center lasting 4 days each (over 3 months)
  • Have glucose tolerance tests, hyperinsulinemic tests, PET-CT scans, and liver ultrasounds
  • Take an FDA-approved medication and placebo tablet for 4-weeks each
  • Receive compensation for your participation

You can participate if you:

  • Are a woman between 18-40 years
  • Have a body mass index (BMI) of 20-45 (calculate your BMI at
  • Are taking oral contraceptives

You can NOT participate if you:

  • Have Type 1 or Type 2 diabetes, hypertension, heart disease, or a psychological condition
  • Have been pregnant, given birth, or have been breastfeeding in the last 12 months
  • Are allergic to mirabegron or a similar drug
  • Drink more than 2 drinks per day or smoke
  • Spend more than 70% of your daily hours outside

The NIH Clinical Center, America's research hospital is located in Bethesda, Maryland. In the Washington, DC metro area, on the Metro red line (Medical Center stop).

For more information:
NIH Clinical Center
Office of Patient Recruitment
800-411-1222 (refer to study 17-DK-0054)
800-877-8339 TTY / ASCII
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Or go online:

Department of Health and Human Services
National Institutes of Health Clinical Center (CC)
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)

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This page last updated on 10/22/2021

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