CONTACT USCall toll free: 1-800-411-1222
(TTY for the deaf or hard of hearing 1-866-411-1010)
Se habla español.
Or e-mail: firstname.lastname@example.org
SEARCH THE STUDIESYou can search the collection of research studies being conducted at the NIH Clinical Center at Search the Studies. In addition, clinicaltrials.gov provides patients, family members, and members of the public easy and free access to information on clinical studies for a wide range of diseases and conditions.
Does adding 1-2 experimental therapies improve treatment of GBM?
NIH Brain Cancer Research
National Cancer Institute researchers in Bethesda, Maryland, are enrolling participants in the very first study of its kind for a type of brain cancer called glioblastoma or GBM. This research study is testing if adding 1-2 experimental therapies (HSPPC-96 or placebo vaccine and pembrolizumab) improves standard treatment for GBM. All treatment and research procedures are provided at no cost. Travel assistance provided for enrolled participants.
During the study:
- After brain surgery at the NIH to remove as much of the tumor as possible, patients will receive the standard treatment for GBM: radiation treatment, and temozolomide (TMZ), an oral chemotherapy drug.
- All patients will also receive an immunotherapy agent called pembrolizumab. The combination of pembrolizumab with standard treatment has been shown to be well-tolerated.
- Some patients will also receive a vaccine made from part of their own tumor. Researchers want to see if adding this personalized cancer vaccine (HSPPC-96) will improve the effect of pembrolizumab.
You may be eligible if you:
- Are an adult who has been recently diagnosed with GBM or have a suspected GBM and are eligible to undergo surgery at the NIH
- Have not already received radiation, chemotherapy or carmustine wafers for your GBM
Location: The NIH Clinical Center, America's research hospital, is conveniently located on the Metro Red Line (Medical Center stop) in Bethesda, Maryland.
For more information, call:
Office of Patient Recruitment
Se habla español
Department of Health and Human Services
National Institutes of Health Clinical Center (CC)
National Cancer Institute (NCI)
Print the Flyer
NOTE: PDF documents require the free Adobe Reader.
This page last updated on 09/04/2018