Researchers at the Obesity and Diabetes Clinical Research Section at the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) in Phoenix, AZ seek generally healthy, adults who are 18-55 years old to participate in an inpatient clinical study. This study investigates the amount of food a person eats when the body's metabolic rate is changed. Investigators want to see how much food is eaten when the body's temperature is cooled. The study will also see if not eating for an entire day will change someone's eating habits the next day.
Study Information:
- Inpatient stay of about 23 days on research unit
- The study consists of several questionnaires, computerized psychological behavior tests, a DXA scan for measurement of body fat, an exercise test on stationary bike, 5 overnight stays in a metabolic chamber, oral glucose tolerance test to determine diabetes, urine collection, and blood draws
- Participants stay in a metabolic chamber cooled to 66 degrees for 24 hours twice during the study
- Participants are asked to eat a specific diet prepared for them during their stay and spend one day (24 hours) fasting, consuming only water
- Two outpatient follow-up visits at 6 months and 1 year
You may be eligible if you are:
- 18-55-year-old males and premenopausal females
- Non-diabetic
- Not pregnant or breast feeding
- Not taking medications that affect metabolism or appetite
- Drug and nicotine screen negative
Compensation is provided.
To learn more, call:
NIH Clinical Center Office of Patient Recruitment
800-411-1222
(TTY users dial 7-1-1)
Email: ccopr@nih.gov
Or go online:
https://go.usa.gov/xzFEQ
Refer to study # 17-DK-N004
Department of Health and Human Services
National Institutes of Health Clinical Center (CC)
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)