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Patient Recruitment

A Randomized, Placebo-Controlled Phase II Study of Multi-Epitope TARP Peptide Autologous Dendritic Cell Vaccination in Men with Stage D0 Prostate Cancer

Have You Been Treated for Prostate Cancer?

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A rising level of prostate specific antigen (PSA) after treatment for prostate cancer can indicate the cancer spreading. If you have been treated for prostate cancer with surgery or radiation after initial diagnosis and have rising levels of PSA, consider participating in a research study at the NIH Clinical Center (NIHCC) in Bethesda, Maryland. Researchers want to explore if using a vaccine targeting at the protein named TARP (the T-cell receptor-γ alternate reading frame protein) expressed in prostate cancer cells helps to slow rising PSA levels; Identifier: NCT02362451. The vaccines will be made using your own blood cells. All study-related tests and procedures will be provided at no cost to you.

You may be eligible if you:

  • Are at least 18 years old;
  • Have been treated for prostate cancer with surgery or radiation;
  • Have a PSA Doubling Time between 3 to 15 months

Study involves:

  • Random assignment to a group that will receive either the TARP vaccine or a placebo;
  • Multiple visits to the NIHCC over 24 month period;
  • Physical exam and blood testing;
  • CT scan and bone scan

The NIH Clinical Center, America's Research Hospital is located on the Metro red line (Medical Center stop) in Bethesda, Maryland.

For more information:
NIH Clinical Center Office of Patient Recruitment
800-411-1222 (refer to study # 15-C-0075)
800-877-8339 TTY / ASCII
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Or go online:

Department of Health and Human Services
National Institutes of Health Clinical Center (CC)
National Cancer Institute (NCI)

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This page last updated on 10/22/2021

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