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SEARCH THE STUDIES

You can search the collection of research studies being conducted at the NIH Clinical Center at Search the Studies. In addition, clinicaltrials.gov provides patients, family members, and members of the public easy and free access to information on clinical studies for a wide range of diseases and conditions.

Patient Recruitment

Have You Been Diagnosed with Chronic Hepatitis B?

A Research Study Seeking Volunteers with Chronic Hepatitis B

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Hepatitis B is a chronic liver infection caused by a virus. There is no cure but the virus can be controlled with antiviral medications. HBV is usually treated with either an oral antiviral medication or peginterferon injection. Researchers at the National Institutes of Health (NIH) in Bethesda, Maryland are testing if taking peginterferon and an oral antiviral medication together is safe and work better to control the virus compared to taking one medication alone.

You may or may not benefit by participating in this study, but we hope the results will help us learn more about hepatitis B and develop future treatments.

Consider participating if you:

  • Are 18 or older and have chronic hepatitis B (HBV)
  • Are currently receiving oral antiviral treatment for HBV

You may NOT participate if you:

  • Have other forms of liver disease including hepatitis C, hepatitis D, liver failure, or liver cancer
  • Have HIV
  • Have received an organ transplant
  • Currently have an alcohol use disorder

Study procedures:

  • You will have a screening visit to determine your eligibility.
  • If found to be eligible you will have an overnight testing visit at the NIH Clinical Center.
  • You will have 2 liver biopsies at the beginning of the study.
  • You will receive peginterferon injection under the skin once a week for 24 weeks by self-injection. This is followed by 48 weeks of follow up testing. Your total participation in this study will be up to 72 weeks (about a year and a half).
  • You will continue with your current HBV oral treatment.

There is no cost for study-related medications, tests, or procedures.

Location: The NIH Clinical Center, America's research hospital, is conveniently located on the Metro Red Line (Medical Center stop) in Bethesda, Maryland. There is no charge for study-related tests or procedures. Compensation and travel assistance may be provided.

For more information, call:
1-800-411-1222
TTY: 1-866-411-1010
Se habla español

Or go online:
clinicaltrials.gov
Refer to study #15-DK-0082

Department of Health and Human Services
National Institutes of Health Clinical Center (CC)
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)

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This page last updated on 10/30/2017

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