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You can search the collection of research studies being conducted at the NIH Clinical Center at Search the Studies. In addition, provides patients, family members, and members of the public easy and free access to information on clinical studies for a wide range of diseases and conditions.

Patient Recruitment

A Research Study for Women with Endometriosis

3 women smiling

Women with Endometriosis and Pelvic Pain

The National Institutes of Health Clinical Center is seeking women with endometriosis and pelvic pain to participate in a research study. Previous research has shown that botulinum toxin injection may reduce pain and spasm of the pelvic floor. However, more research is needed to test if botulinum toxin is an effective treatment for pelvic floor spasm in women with pelvic pain.

Study involves:

  • Two or more outpatient visits to the NIH Clinical Center over a period of one month.
  • Two follow up visits following the study injection.
  • Receiving either botulinum toxin or placebo (salt water) injection.
  • After the study injection, you may receive one botulinum toxin injection during the one year follow-up period.
  • Study-related tests and medications are provided at no cost.

You may be eligible if you:

  • Are a woman, 18-50 years old.
  • Have been surgically diagnosed with endometriosis and have persistent pelvic pain.

You may not be eligible if you:

  • Have had a hysterectomy.
  • Have a history of urinary incontinence, fecal incontinence, or pelvic prolapse.
  • Have any other conditions which may be causing pelvic pain such as gastrointestinal, psychological disorders, fibromyalgia or chronic fatigue syndrome.
  • Have an allergy to albumin or botulinum toxin.

Location: The NIH Clinical Center, America's research hospital, is conveniently located on the Metro Red Line (Medical Center stop) in Bethesda, Maryland. Parking is provided at no cost.

For more information:
Call: 1-800-411-1222
TTY: 1-866-411-1010
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Or go online:
Refer to study # 12-N-0083

Department of Health and Human Services
National Institutes of Health Clinical Center (CC)
National Institute of Neurological Disorders and Stroke (NINDS)

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This page last updated on 09/07/2017

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