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Director, Genomics Section, Microbiology Service
BA, Wesleyan University
MD, Harvard Medical School
PhD, Harvard University
Investigator, Lasker Clinical Research Scholar
Chief, Bacterial Pathogenesis and Antimicrobial Resistance Unit,
Laboratory of Clinical Immunology and Microbiology, NIAID
Dr. John Dekker is an Investigator and Chief of the Bacterial Pathogenesis and Antimicrobial Resistance Unit in the Laboratory of Clinical Immunology and Microbiology within the National Institute of Allergy and Infectious Diseases. He also serves as the Director of the Genomics Section in the Microbiology Service, Department of Laboratory Medicine, NIH Clinical Center.
Dr. Dekker received his MD and PhD degrees from Harvard Medical School through the NIH Medical Scientist Training Program. He completed Pathology residency and fellowship training in Medical Microbiology at Massachusetts General Hospital, and is board-certified in Clinical Pathology and Medical Microbiology through the American Board of Pathology.
In 2013, he joined the NIH Clinical Center as a senior staff member of the Microbiology Service in the Department of Laboratory Medicine. In this role, he co-directed the Bacteriology, Specimen Processing, Parasitology and Molecular Epidemiology sections before serving as Acting Chief of the Microbiology Service in 2018.
In 2018, he joined NIAID as an Investigator and Lasker Clinical Research Scholar, and heads the Bacterial Pathogenesis and Antimicrobial Resistance Unit within the Laboratory for Clinical Immunology and Microbiology. In addition, he oversees the newly created Genomics Section within the Microbiology Service, DLM, which focuses on development of next-generation sequencing based approaches with applications in epidemiology and infectious diseases.
Dr. Dekker serves on the Clinical Center Hospital Infection Control Committee and the National Institute of Allergy and Infectious Diseases’ Infectious Disease Fellowship Committee. He has served on FDA Anti-Infective Drug Advisory Committees in 2013 and 2014. He is also a member of the Editorial Board for Journal of Clinical Microbiology.
In 2016, Dr. Dekker received the prestigious Beckman-Coulter Young Investigator award from the American Society for Microbiology, and has received an NIH Clinical Center CEO Award in 2017 for developing diagnostic methods using Next Generation Sequencing for improved rapid infectious disease and antibiotic resistance diagnosis.
Dr. Dekker’s research interests are in the areas of (1) mechanisms of antimicrobial resistance in bacteria, (2) emergence and in vivo evolution of MDR phenotypes in the natural context of human infection, and (3) development of novel genomic and proteomic assays for rapid resistance diagnostics.
See more about Dr. Dekker and his research.
Lemon JK, Khil PP, Frank KM, Dekker JP. Rapid Nanopore Sequencing of Plasmids and Resistance Gene Detection in Clinical Isolates. Journal Clinical Microbiology, 2017, 55(12):3530-3543.
Wang H, Drake SK, Youn, JH, Rosenberg, AZ, Yong C, Gucek M, Suffredini AF, Dekker, JP. Peptide Markers for Rapid Detection of KPC Carbapenemase by LC-MS/MS. Scientific Reports, 2017, May 31;7(1):2531.
Wang H, Drake SK, Yong C, Gucek M, Tropea M, Lyes M, Rosenberg AZ, Soderblom E, Mayer-Salmon M, Arthur Moseley M, Dekker JP, and Suffredini AF. A Genoproteomic Approach to Detect Peptide Markers of Bacterial Respiratory Pathogens. Clinical Chemistry, 2017, Epub 63:8.
Dekker JP. Molecular Assay Validation Using Genomic Sequence Databases. Journal Clinical Microbiology, 2016, 54(12):2854-2856.
Dekker JP, Frank KM. 2016. Next Generation Epidemiology: Using Real-Time cgMLST to Support Infection Control Policy. Journal Clinical Microbiology, 2016, 54(12):2850-2853.
Wang H, Drake SK, Yong C, Gucek M, Tropea M, Rosenberg AZ, Dekker JP, Suffredini AF. A Novel Peptidomic Approach to Strain Typing of Clinical Acinetobacter baumannii Isolates Using Mass Spectrometry. Clinical Chemistry, 2016, 62:866-875.
Snesrud E, He S, Chandler M, Dekker JP, Hickman AB, McGann P, Dyda F. A Model for Transposition of the Colistin Resistance Gene mcr-1 by ISApl1. Antimicrobial Agents Chemotherapy, 2016, 60(11):6973-6976.
He S, Hickman AB, Varani AM, Siguier P, Chandler M, Dekker JP, Dyda F. Insertion Sequence IS26 Reorganizes Plasmids in Clinically Isolated Multidrug-Resistant Bacteria by Replicative Transposition. MBio, 2015, 6:e00762.
Lau AF, Wang H, Weingarten RA, Drake SK, Suffredini AF, Garfield MK, Chen Y, Gucek M, Youn JH, Stock F, Tso H, DeLeo J, Cimino JJ, Frank KM, Dekker JP. A rapid matrix-assisted laser desorption ionization-time of flight mass spectrometry-based method for single-plasmid tracking in an outbreak of carbapenem-resistant Enterobacteriaceae. Journal Clinical Microbiology, 2014, 52:2804-2812.
Visit PubMed for a complete publication listing.
- 2017 NIH Clinical Center CEO Award for developing diagnostic methods using Next Generation Sequencing for improved rapid infectious disease and antibiotic resistance diagnosis
- 2016 Beckman-Coulter Young Investigator Award – American Society for Microbiology
- 2015 NIH Director’s Award (group recipient) – NIH Ebola Patient Care Response Team
- 2013 NIH Clinical Center Director’s Award (group recipient) – Ebola Virus Laboratory Support
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This page last updated on 03/14/2019