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Sickle Cell Anemia:
Moving from Pain to Cure

Mark Gladwin, M.D.
Senior Investigator
Critical Care Medicine Dept.
NIH Clinical Center


Tuesday, September 30, 2003 • 7 pm
Masur Auditorium • NIH Clinical Center

Photo of Dr. Gladwin

Senior Investigator Dr. Mark Gladwin leads the Sickle Cell/Nitric Oxide Therapeutic Section in the Critical Care Medicine Department at the NIH Clinical Center. His research endeavors focus on understanding the role of lung complications in adults with sickle cell disease and evaluating the role of current (hydroxyurea) and future (nitric oxide) therapies in sickle cell disease treatment.

After receiving his Bachelor of Science and Doctor of Medicine degrees at the University of Miami he completed an internship and chief residency in internal medicine at the Oregon Health Sciences University in Portland, Oregon. He then served in three fellowships, as a Critical Care Fellow with the Critical Care Medicine Department at the NIH Clinical Center; a Pulmonary-Critical Care Fellow in the Pulmonary Division of the University of Washington in Seattle; and as a Senior Research Fellow in critical care medicine, returning to NIH in 1998. From 1995 to 2000 Dr. Gladwin was on active duty as a Commander in the U. S. Public Health Service Commissioned Corps. He has served as Section Head for the Sickle Cell/Nitric Oxide Therapeutic Section with the NIH Clinical Center's Critical Care Medicine department since 2001.

Dr. Gladwin's awards and accolades cover mentoring, teaching and scholarship. These include academic merit and honors scholarships from the University of Miami and teaching awards from the Oregon Health Sciences University and professional organizations such as the American College of Physicians, American Thoracic Society and American Heart Association. His mentoring and research leadership efforts have been recognized by the Fellowship Program in Academic Medicine for Minority Students, the Clinical Center and NIH.

As founder and director of the Unity Healthcare Asthma/Pulmonary Clinic Mission in Washington, D.C., Dr. Gladwin delivers pulmonary subspecialty care to homeless and indigent patients through two community clinics. With the support of NIH's Office for Research in Minority Health and the Clinical Center's Critical Care Medicine Department he has established programmatic relationships between minority patients and NIH clinical research protocols

He is the principal or associate investigator on more than a half dozen concurrent studies researching potential interventional therapies for the management of sickle cell disease symptoms and complications. He has received research grants from NIH's Office for Research in Minority Health and both the Bedside-to-Bench and Cooperative Research and Development Agreement programs.

A prolific lecturer and writer, Dr. Gladwin is recognized as a diplomat in Pulmonary Disease with the American Board of Pulmonary Medicine and in Critical Care Medicine with the American Board of Critical Care Medicine, and is board certified as an internal medicine specialist.

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