Phagocyte Function
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The Neutrophil Monitoring Laboratory (NML) provides both clinical and basic research support to investigators in NIAID. The NLM primary mission is to provide CLIA-certified studies of phagocytic cell function on samples isolated from patients with suspected host defense defects. Studies focus on samples from patients seen at the NIH Clinical Center but with special approval also from samples shipped by express mail. Assays include determinations of reactive oxygen intermediates, staphylocidal activity, neutrophil adherence, chemotaxis, release of granular proteins and alteration of surface marker expression, cytokine expression among others. Gene sequencing is provided on patients suspected of specific defects studies at NIAID.
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Douglas Kuhns Doug.kuhns@nih.gov 301.846.6378
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