Human brain derived multipotential progenitor cells have been identified, isolated and propagated in culture from various gestational ages. The progenitor cells can be directed to different lineages by providing extracellular signals as growth factors in order to direct differentiation to astrocytes, neurons, or oligodendrocytes. The progenitor cells can be maintained through many cell divisions when propagated under culture conditions using specific stem cell factors.

Gene Major, Ph.D.
majorg@ninds.nih.gov
301.496.1635

http://neuroscience.nih.gov/Lab.asp?Org_ID=530