Dr. Pham is a graduate of George Washington University, where he earned a BS degree in electrical engineering. He also earned MSE and PhD degrees in electrical engineering from Johns Hopkins University. He received both pre-doctoral and post-doctoral training at the National Institute on Aging, where he was honored with the Fellow's Award for Research Excellence. Before joining the Center for Neuroscience and Regenerative Medicine (CNRM) and NIH, he was a Neuroradiology faculty member with Johns Hopkins University. Dr. Pham retains adjunct appointments with the Department of Electrical and Computer Engineering and the Department of Radiology at Johns Hopkins University. He also holds an appointment with Uniformed Services University Department of Radiology and Radiological Sciences.
Dr. Pham is currently the director of the Image Processing Core for CNRM. His research interests include image processing and computer vision with application to biomedical imaging. He is particularly interested in the development and application of image analysis algorithms using stochastic and variational models for the quantitative assessment of traumatic brain injury, multiple sclerosis, and other neurodegenerative diseases. His expertise within the field of medical image processing has led to invitations to write chapters and review articles for the Annual Review of Biomedical Engineering, the Handbook of Medical Imaging from SPIE Press, the Handbook of Medical Imaging from Elsevier, and IEEE Signal Processing Magazine.
N. Li, W.-T. Wang, P. Sati, D.L. Pham, J.A. Butman, "Quantitative evaluation of phase processing approaches in susceptibility weighted imaging," to be presented at SPIE Medical Imaging, Feb. 4-9, San Diego, CA, 2012.
P.L. Bazin, C. Ye, J.A. Bogovic, N. Shiee, D.S. Reich, J.L. Prince, D.L. Pham, "Direct Segmentation of the Major White Matter Tracts in Diffusion Tensor Images," NeuroImage, 58(2): 458-468,2011.
A. Mashayekh, D.L. Pham, D.M. Yousem, M. Dizon, P.B. Barker, D.D.M. Lin "Effects of Ginkgo biloba on cerebral blood flow assessed by quantitative MR perfusion imaging: a pilot study," Neuroradiology, 53(3): 185-191, 2011.
N. Shiee, P.-L. Bazin, J.L. Cuzzocreo, A. Blitz, D.L. Pham, "Segmentation of brain images using adaptive atlases with application to ventriculomegaly," presented at the 22nd International Conference on Information Processing in Medical Imaging (IPMI), Irsee, Germany, July 3-8 2011.
D.L. Pham, P.-L. Bazin, J.L. Prince, "Digital Topology in Brain Imaging: Creating Anatomically Consistent Representations of the Human Brain," IEEE Signal Processing Magazine, 27(4): 51-59, 2010.
V. Rao, C.A. Munro, P. Rosenberg, J. Ward, M. Bertrand, M. Degoankar, A Horska, D.L Pham, D.M. Yousem, P.B. Barker, "Neuroanatomical Correlates of Depression in Post Traumatic Brain Injury: Preliminary Results of a Pilot Study," The Journal of Neuropsychiatry and Clinical Neurosciences, 22(2): 231-235, 2010.
B.C. Lucas, J.A. Bogovic, A. Carass, P.-L. Bazin, J.L. Prince, D.L. Pham, B.A. Landman, "The Java Image Science Toolkit (JIST) for Rapid Prototyping and Publishing of Neuroimaging Software," Neuroinformatics, 8(1): 5-17, 2010.
A. Ozturk, S.A. Smith, E.M. Gordon-Lipkin, D.M. Harrison, N. Shiee, D.L. Pham, B.S. Caffo, P.A. Calabresi, D.S. Reich, "MRI of the Corpus Callosum in Multiple Sclerosis: Association with Disability " Multiple Sclerosis, 16(2): 166-177, 2010.
N. Shiee, P.-L. Bazin, A. Ozturk, P.A. Calabresi, D.S. Reich, D.L. Pham, "A Topology-Preserving Approach to the Segmentation of Brain Images with Multiple Sclerosis Lesions" NeuroImage, 49(2): 1524-1535, 2010.
S. Roy, A. Carass, N. Shiee, D.L. Pham, J.L. Prince, "MR Contrast Synthesis for Lesion Segmentation," presented at the IEEE International Symposium on Biomedical Imaging (ISBI): From Nano to Macro, in Rotterdam, The Netherlands, April 14-17, 2010.
N. Shiee, P.-L. Bazin, D.S. Reich, D.L. Pham, "Automated Reconstruction of the Cerebral Cortex in Multiple Sclerosis Patients," Proceedings of the 6th International Symposium on Biomedical Imaging: From Macro to Nano, pp. 1334-1337, in Boston, Massachusetts, June, 2009.
B. Kishore, P.-L. Bazin, D.L. Pham, "BrainIACS : A System for Web-based Medical Image Processing," presented at SPIE Medical Imaging: Advance PACS-based Imaging Informatics and Therapeutic Applications in Orlando, FL, Feb. 7-12, vol. 7264: 72460P1-9, 2009.
D.L. Pham, P.-L. Bazin, "Unsupervised Tissue Classification," Handbook of Medical Image Processing and Analysis, 2nd Edition, Isaac Bankman (ed.), Elsevier, Burlington, MA, pp. 209-221, 2008.
C. Krishnan, A.I. Kaplin, R.A. Brodsky, D.B. Drachman, R.J. Jones, D.L. Pham, N.D. Richert, C.A. Pardo, D.M. Yousem, E. Hammond, M. Quigg, C. Trecker, J.C. McArthur, A. Nath, B.M. Greenberg, P.A. Calabresi, D.A. Kerr, "Reduction of Disease Activity and Disability With High-Dose Cyclophosphamide in Patients With Aggressive Multiple Sclerosis," Archives of Neurology, 65(8):1044-1051, 2008.
P.-L. Bazin, D.L. Pham, "Homeomorphic Brain Image Segmentation with Topological and Statistical Atlases," Medical Image Analysis, 12(5):616-625, 2008.
J.C. Carter, D.C. Lanham, D.L. Pham, G. Bibat, S. Naidu, W.E. Kaufmann, "Selective Cerebral Volume Reduction in Rett Syndrome: a Multiple Approach MRI Study," American Journal of Neuroradiology, 29(3): 436-441, American Journal of Neuroradiology, March 2008.
P.-L. Bazin, D.L. Pham, "Topology Correction of Segmented Medical Images using a Fast Marching Algorithm," Computer Methods and Programs in Biomedicine, 88(2): 182-290, Nov 2007.
P.-L. Bazin, J.L. Cuzzocreo, M.A. Yassa, W. Gandler, M.J. McAuliffe, S.S. Bassett, D.L. Pham, "Volumetric neuroimage analysis extensions for the MIPAV software package," Journal of Neuroscience Methods 165(1): 111-121, Sept 2007.
P.-L. Bazin, L.M. Ellingsen and D.L. Pham, "Digital Homeomorphisms in Deformable Registration", presented at the 20th International Conference on Information Processing in Medical Imaging, in Kerkrade, NL, July 2007, LNCS 4584, pp. 211-222, 2007.