2011
http://www.ncbi.nlm.nih.gov/pubmed/21295032
Kim H, White CD, Sacks DB. IQGAP1 in microbial pathogenesis: Targeting the actin cytoskeleton [Review]. FEBS Lett 2011; 585:723-729.
http://www.ncbi.nlm.nih.gov/pubmed/21185879
White CD, Li Z, Sacks DB. Calmodulin binds HER2 and modulates HER2 signaling. Biochim Biophys Acta 2011, in the press.
http://www.ncbi.nlm.nih.gov/pubmed/21349850
McNulty DE, Li Z, White CD, Sacks DB, Annan RS. MAP kinase scaffold IQGAP1 binds the EGF receptor and modulates its activation. J Biol Chem 2011, in the press.
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2010
http://www.ncbi.nlm.nih.gov/pubmed/20977743
White CD, Khurana H, Gnatenko DV, Li Z, Odze RD, Sacks DB, Schmidt VA. IQGAP1 and IQGAP2 are reciprocally altered in hepatocellular carcinoma. BMC Gastroenterology 2010; 10:125 doi: 10.1186/1471-230X-10-125.
http://www.ncbi.nlm.nih.gov/pubmed/20811982
White CD, Sacks DB. Regulation of MAPKs by calcium. Methods Mol Biol 2010; 661:151-165.
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2009
http://www.ncbi.nlm.nih.gov/pubmed/19433088
White CD, Brown MD, Sacks DB. IQGAPs in Cancer: A Family of Scaffold Proteins Underlying Tumorigenesis. FEBS Lett 2009; 583:1817-24.
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2668224/pdf/nihms99441.pdf 
(890 KB)
Brown MD, Sacks DB. Protein scaffolds in MAP kinase signalling [Review]. Cell Signal 2009; 21:462-9.
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2008
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2585478/pdf/pone.0003848.pdf (1.61 MB)
Meyer RD, Sacks DB, Rahimi N. IQGAP1-dependent signaling pathway regulates endothelial cell proliferation and angiogenesis. PLoS ONE 2008; 3:e3848.
http://www.jbc.org/content/283/50/35212.full.pdf (784 KB) [disclaimer]
Brown MD, Bry L, Li Z, Sacks DB. Actin pedestal formation by EPEC is regulated by IQGAP1, calcium and calmodulin. J Biol Chem 2008; 283:35212-35222.
http://www.ncbi.nlm.nih.gov/pubmed/18491054
Brown MD, Sacks DB. Compartmentalised MAPK Pathways [Review]. Handb Exp Pharmacol 2008; 186:205-235.
Brown MD, Sacks DB. Adaptor proteins, in Encyclopedia of Molecular Pharmacology, 2nd ed., S. Offermanns and W. Rosenthal, Editors. 2008, Springer: Amsterdam. p. 15-19.
http://www.jbc.org/content/283/34/22972.full.pdf (606 KB) [disclaimer]
Ren JG, Li Z, Sacks DB. IQGAP1 integrates Ca2+/calmodulin and B-Raf signaling. J Biol Chem 2008; 283:22972-22982.
http://www.jbc.org/content/283/3/1692.full.pdf (542 KB) [disclaimer]
Owen D, Campbell LJ, Littlefield K, Evetts KA, Li Z, Sacks DB, Lowe PN, Mott HR. The IQGAP1-Rac1 and IQGAP1-Cdc42 interactions: interfaces differ between the complexes. J Biol Chem 2008; 283:1692-1704.
http://www.jbc.org/content/283/2/1008.full.pdf (479 KB) [disclaimer]
Jadeski L, Mataraza JM, Jeong HW, Li Z, Sacks DB. IQGAP1 stimulates proliferation and enhances tumourigenesis of human breast epithelial cells. J Biol Chem 2008; 283:1008-1017.
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2007
http://www.jbc.org/content/282/41/30265.full.pdf (573 KB) [disclaimer]
Brown MD, Bry L, Li Z, Sacks DB. IQGAP1 regulates Salmonella invasion through interactions with actin Rac1 and Cdc42. J Biol Chem 2007; 282:30265-30272.
http://www.pnas.org/content/104/25/10465.full.pdf (759 KB) [disclaimer]
Ren JG, Li Z, Sacks DB. IQGAP1 modulates activation of B-Raf. Proc Natl Acad Sci USA 2007; 104:10465-10469.
http://www.jbc.org/content/282/28/20752.full.pdf (517 KB) [disclaimer]
Jeong HW, Li Z, Brown MD, Sacks DB. IQGAP1 binds Rap1 and modulates its activity. J Biol Chem 2007; 282:20752-20762.
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1992526/pdf/nihms28707.pdf (810 KB)
Mataraza JM, Li Z, Jeong HW, Brown MD, Sacks DB. Multiple proteins mediate IQGAP1-stimulated cell migration. Cell Signal 2007; 19:1857-1865.
http://www.ncbi.nlm.nih.gov/pubmed/17070670
Li L, Sacks DB. Functional interactions between calmodulin and estrogen receptor-a [Review]. Cell Signal 2007; 19:439-443.
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2006
http://www.ncbi.nlm.nih.gov/pubmed/17052209
Sacks DB. The role of scaffold proteins in MEK/ERK signalling. Biochem Soc Trans, 2006; 34:833-836.
http://www.ncbi.nlm.nih.gov/pubmed/16595175
Brown MD, Sacks DB. IQGAP1 in cellular signaling: bridging the GAP. Trends Cell Biol 2006; 16(5) 242-9.
http://www.jbc.org/content/281/4/1978.full.pdf (386 KB) [disclaimer]
Li L, Li Z, Howley PM, Sacks DB. E6AP and calmodulin reciprocally regulate estrogen receptors stability. J Biol Chem 2006; 281(4):1978-85.
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2005
http://mcb.asm.org/cgi/reprint/25/18/7940.pdf (502 KB) [disclaimer]
Roy M, Li Z, Sacks DB. IQGAP1 is a scaffold for mitogen-activated protein kinase signaling. Mol Cell Biol 2005;25:7940-52.
http://www.jbc.org/content/280/41/34548.full.pdf (518 KB) [disclaimer]
Ren JG, Li Z, Crimmins DL, Sacks DB. Self-association of IQGAP1: characterization and functional sequelae. J Biol Chem 2005;280:34548-57.
http://www.jbc.org/content/280/13/13097.full.pdf (330 KB) [disclaimer]
Li L, Li Z, Sacks DB. The transcriptional activity of estrogen receptor-alpha is dependent on Ca2+/calmodulin. J Biol Chem. 2005; 280:13097-104.
http://www.jbc.org/content/280/14/13871.full.pdf (418 KB) [disclaimer]
Li Z, McNulty DE, Marler KJ, Lim L, Hall C, Annan RS, Sacks DB. IQGAP1 promotes neurite outgrowth in a phosphorylation-dependent manner. J Biol Chem 2005; 280:13871-8.
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2004
http://www.jbc.org/content/279/17/17329.full.pdf (388 KB) [disclaimer]
Roy M, Li Z, Sacks DB. IQGAP1 binds ERK2 and modulates its activity. J Biol Chem 2004; 279:17329-37.
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2003
http://www.jbc.org/content/278/42/41237.full.pdf (573 KB) [disclaimer]
Mataraza JM, Briggs MW, Li Z, Entwistle A, Ridley AJ, Sacks DB. IQGAP1 promotes cell motility and invasion. J Biol Chem 2003; 278(42):41237-45.
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1319206/pdf/4-embor867.pdf (52 KB)
Briggs MW, Sacks DB. IQGAP proteins are integral components of cytoskeletal regulation [Review]. EMBO Rep. 2003; 4:571-4.
http://www.ncbi.nlm.nih.gov/pubmed/12729888
Briggs MW, Sacks DB. IQGAP1 as signal integrator: Ca2+, calmodulin, Cdc42 and the cytoskeleton [Review]. FEBS Lett 2003; 542:7-11.
http://www.ncbi.nlm.nih.gov/pubmed/12745076
Mataraza JM, Briggs MW, Li Z, Frank R, Sacks DB. Identification and characterization of the Cdc42-binding site of IQGAP1. Biochem Biophys Res Commun 2003; 305:315-321.
http://www.jbc.org/content/278/6/4347.full.pdf (276 KB) [disclaimer]
Li Z, Sacks DB. Elucidation of the interaction of calmodulin with the IQ motifs of IQGAP1. J Biol Chem 2003; 278:4347-4352.
http://www.jbc.org/content/278/2/1195.full.pdf (267 KB) [disclaimer]
Li L, Li Z, Sacks DB. Calmodulin regulates the transcriptional activity of estrogen receptors: selective inhibition of calmodulin function in subcellular compartments. J Biol Chem 2003; 278:1195-1200.
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2002
http://www.jbc.org/content/277/27/24753.full.pdf (955 KB) [disclaimer]
Swart-Mataraza JM, Li Z, Sacks DB. IQGAP1 is a component of Cdc42 signaling to the cytoskeleton. J Biol Chem 2002; 277:24753-24763.
http://www.jbc.org/content/277/9/7453.full.pdf (662 KB) [disclaimer]
Briggs MW, Li Z, Sacks DB. IQGAP1-mediated stimulation of transcriptional co-activation by beta-catenin is modulated by calmodulin. J Biol Chem. 2002; 277:7453-65.
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2001
http://www.jbc.org/content/276/51/48425.full.pdf (311 KB) [disclaimer]
Sokol SY, Li Z, Sacks DB. The effect of IQGAP1 on Xenopus embryonic ectoderm requires Cdc42. J Biol Chem. 2001; 276:48425-30.
http://www.jbc.org/content/276/20/17354.full.pdf (255 KB) [disclaimer]
Li Z, Joyal JL, Sacks DB. Calmodulin enhances the stability of the estrogen receptor. J Biol Chem. 2001; 276:17354-60.
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2000
http://www.jbc.org/content/275/47/36999.full.pdf (666 KB) [disclaimer]
Kim SH, Li Z, Sacks DB. E-cadherin-mediated cell-cell attachment activates Cdc42. J Biol Chem 2000; 275: 36999-37005.
http://www.ncbi.nlm.nih.gov/pubmed/10819975
Li Z, Joyal JL, Sacks DB. Binding of IRS proteins to calmodulin is enhanced in insulin resistance. Biochemistry 2000; 39:5089-5096.
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1999
http://www.jbc.org/content/274/53/37885.full.pdf (1.08 MB) [disclaimer]
Li Z, Kim SH, Higgins JM, Brenner MB, Sacks DB . IQGAP1 and calmodulin modulate E-cadherin function. J Biol Chem 1999; 274:37885-37892.
http://www.jbc.org/content/274/1/464.full.pdf (302 KB) [disclaimer]
Ho YD, Joyal JL, Li Z, Sacks DB. IQGAP1 integrates Ca2+ /calmodulin and Cdc42 signaling. J Biol Chem 1999; 274:464-470.
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1997
http://www.jbc.org/content/272/45/28183.full.pdf (326 KB) [disclaimer]
Joyal JL, Burks DJ, Pons S, Matter WF, Vlahos CJ, White MF, Sacks DB . Calmodulin activates phosphatidylinositol 3-kinase. J Biol Chem 1997; 272:28183-28186.
http://www.jbc.org/content/272/24/15419.full.pdf (319 KB) [disclaimer]
Joyal JL, Annan RA, Ho YD, Huddleston ME, Carr SA, Hart MJ, Sacks DB . Calmodulin modulates the interaction between IQGAP1 and Cdc42: Identification of IQGAP1 by nanoelectro-spray tandem mass spectrometry. J Biol Chem 1997; 272:15419-15425.
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1996
http://www.whitelabs.org/publications/pdf/1996/MFW130.pdf (446 KB) [disclaimer]
Munshi HG, Burks DJ, Joyal JL, White MF, Sacks DB . Ca2+ regulates calmodulin binding to IQ motifs in IRS-1. Biochemistry 1996; 35:15883-15889.
http://www.ncbi.nlm.nih.gov/pubmed/8639568
Joyal JL, Crimmins DL, Thoma RS, Sacks DB. Identification of insulin-stimulated phosphorylation sites on calmodulin. Biochemistry 1996; 35:6267-6275.
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1995
http://www.biochemj.org/bj/312/0197/3120197.pdf (1.56 MB) [disclaimer]
Sacks DB, Mazus B, Joyal JL. The activity of calmodulin is altered by phosphorylation: modulation of calmodulin function by the site of phosphate incorporation. Biochem J 1995; 312:197-204.
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1994
http://www.jbc.org/content/269/47/30039.full.pdf (8.95 MB) [disclaimer]
Joyal JL, Sacks DB. Insulin-dependent phosphorylation of calmodulin in rat hepatocytes. J Biol Chem 1994; 269:30039-30048.
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1993
http://www.jbc.org/content/268/24/18157.full.pdf (4.67 MB) [disclaimer]
Tanasijevic MJ, Myers MG Jr, Thoma RS, Crimmins DL, White MF, Sacks DB . Phosphorylation of the insulin receptor substrate IRS-1 by casein kinase II. J Biol Chem 1993; 268:18157-18166.
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1992
http://www.biochemj.org/bj/286/0211/2860211.pdf (1.47 MB) [disclaimer]
Sacks DB, Davis HW, Crimmins DL, McDonald JM. Insulin-stimulated phosphorylation of calmodulin. Biochem J 1992; 286:211-216.
http://www.biochemj.org/bj/283/0021/2830021.pdf (841 KB) [disclaimer]
Sacks DB, Davis HW, Sheehan EL, Williams JP, Garcia JG, McDonald JM. Phosphorylation by casein kinase II alters the biological activity of calmodulin. Biochem J 1992; 283:21-24.
http://www.ncbi.nlm.nih.gov/pubmed/1420160
Reddy GP, Reed WC, Sheehan EL, Sacks DB. Calmodulin-specific monoclonal antibodies inhibit DNA replication in mammalian cells. Biochemistry 1992; 31:10426-10430.
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1991
http://www.ncbi.nlm.nih.gov/pubmed/1862939
Sacks DB, Porter SE, Ladenson JH, McDonald JM . Monoclonal antibody to calmodulin: Development, characterization and comparison with polyclonal anti-calmodulin antibodies. Anal Biochem 1991; 194:369-377.
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1989
http://www.ncbi.nlm.nih.gov/pubmed/2660785
Sacks DB, Glenn KC, McDonald JM. The carboxyl terminal segment of the c-Ki-ras 2 gene product mediates insulin-stimulated phosphorylation of calmodulin and stimulates insulin-dependant autophosphorylation of insulin receptor. Biochem Biophys Res Commun. 1989;161:399-405.
www.biochemj.org/bj/263/0813/2630813.pdf (2.11 MB) [disclaimer]
Fujita-Yamaguchi Y, Sacks DB, McDonald JM, Sahal D, Kathuria S. Effect of basic polycations and proteins on purified insulin receptor. Insulin-independent activation of the insulin receptor tyrosine-specific protein kinase by poly(L-lysine). Biochem J 1989; 263:813-822.
http://www.biochemj.org/bj/263/0803/2630803.pdf (2.21 MB) [disclaimer]
Sacks DB, Fujita-Yamaguchi Y, Gale RD, McDonald JM. Tyrosine-specific phosphorylation of calmodulin by the insulin receptor kinase purified from human placenta. Biochem J 1989; 263:803-812.
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1988
http://www.jbc.org/content/269/47/30039.full.pdf (8.95 MB) [disclaimer]
Sacks DB, McDonald JM. Insulin-stimulated phosphorylation of calmodulin by rat liver insulin receptor preparations. J Biol Chem 1988; 263:2377-2383.
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