Deadlines and Submission Instructions

Each proposal should:

• include an abstract of the project
• identify one principal clinical or translational investigator and one principal basic scientist
• demonstrate evidence that the proposal was particularly stimulated by the availability of this special funding mechanism
• include budget details per Attachment 2
• not exceed five pages in length. Note that proposals >5 pages will not be considered; this limit does not include abstract or references)
• satisfy the following criteria:
• inter-institute collaborations are preferred (i.e., proposals should involve investigators from more than one IC)
• collaborations between intramural and extramural investigators will receive priority review
• quality of science should be high
• promise to evolve into an active clinical protocol should be clearly articulated
• the plan for use of patients (not just tissue specimens) in the bedside component should be defined
• the potential to result in understanding an important disease process or lead to new therapeutic intervention should be explained
  proposals should have bench and bedside components clearly related in a translational sense – the components should complement each other – one should lead logically to the next, and both components should be strongly developed
• the work should be a truly new initiative, not a funding request for a ‘work in progress’
  

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