Biosketch

Dr. Naomi O'Grady is a staff clinician in the Clinical Center's Critical Care Medicine Department and the medical director of the CC's Procedures, Vascular Access, and Conscious Sedation Services. She also is an attending physician with the Pediatric Critical Care Medicine Department of the Children's National Medical Center and an assistant professor in the Department of Internal Medicine's Division of Infectious Diseases at Johns Hopkins University School of Medicine.

She obtained her undergraduate degree from University of Michigan and her medical degree at Ohio State University, then completed fellowships with NIH, and Johns Hopkins University, before returning to NIH in 1999.

Her research focuses on strategies to reduce the incidence of antimicrobial resistant pathogens in the ICU, and catheter-related blood stream infections.

Dr. O'Grady is currently the Co-Chair of the American Board of Internal Medicine Subspecialty Board for Critical Care Medicine, and has served on the institutional review board of the National Institute of Allergy and Infectious Diseases and the Disaster Planning and Response Task Force of the Society of Critical Care Medicine. She is a fellow of the Infectious Diseases Society and of the American College of Critical Care Medicine.

Honors and Awards

Society of Critical Care Medicine Presidential Citation, 2002, 2000, 1997; Fellow's Award for Research Excellence, 1998; USPHS Achievement Medal,1998; Infectious Disease Society of America Kass Fellowship,1992; National Heart, Lung and Blood Institute Research Fellowship,1988; Samuel J. Roessler Research Scholarship, 1987

Selected Publications

BOOKS/BOOK CHAPTERS

O'Grady NP, Masur H. Antibacterial therapy in the intensive care unit. In: Parrillo (ed), Current Therapy in Critical Care Medicine, Third edition, St. Louis, Missouri: Mosby Yearbook. 1997; 289-295

O'Grady NP, Suffredini AF. Pathophysiologic responses to endotoxin in man. In: Braude, Morrison, Opal, and Vogel (eds), Endotoxin in Man. Third edition, New York, New York: Marcel Decker. 1998; section XII, Chapter 61

Guillet-Agrawal A, O'Grady NP. Biologic agents and syndromes in: Fundamentals of Disaster Management. Society of Critical Care Medicine. 2003

O'Grady and Pittet: Catheter-Related Infections in the Critically Ill. Boston, MA: Kluwer 2004

O'Grady NP. Novel strategies for preventing catheter-related infections in the intensive care unit. In: O'Grady and Pittet (eds)Catheter-Related Infections in the Critically Ill. Boston, MA: Kluwer 2004

Gutierrez D, O'Grady NP. Central venous access devices. In: Abraham, Allegra and Gulley (eds) Bethesda Handbook of Clinical Oncology. Philadelphia, PA, Lippincott Williams and Wilkins 2005

O'Grady NP. Managing and preventing catheter-related infections in oncology patients in: The Hematology-Oncology Sourcebook. Boston, MA McGraw-Hill In Press

JOURNAL ARTICLES

O'Grady NP, Gerberding JL, Weinstein RA, Masur H. Patient safety and the science of prevention: The time for implementing the guidelines for the prevention of catheter related infection is now. Crit Care Med 2003 Jan;31(1):291-2.

Salgado CD, O'Grady NP, Farr BT. Strategies for control of antimicrobial resistance in intensive care. Crit Care Med 2005 Sept;33 (10): 1864-78.

O'Grady NP. Review: paired quantitative blood cultures most accurately detect intravascular device-related bloodstream infection. ACP J Club 2005 Nov-Dec; 143(3):77.

Prasad R, Quezado Z, St. Andre A, O'Grady NP. Fires in the Operating Room: Awareness is the key to prevention. Anesth Analg 2006 Jan; 102(1):172-4.

Huskins WC, O'Grady NP, Samore M, Wallace D, Goldmann DA, Pappas PG. Design and methodology of the strategies to reduce transmission of antimicrobial resistant bacteria in intensive care units (STAR-ICU) trial. Infect Control Hosp Epidemiol. 2007 Feb;28(2):245-6.

O'Grady NP, Barie PS, Bartlett JG, Bleck T, Carroll K, Kalil AC, Linden P, Maki DG, Nierman D, Pasculle W, and Masur H. Guidelines for evaluation of new fever in critically ill adult patients: 2008 update from the American College of Critical Care Medicine and the Infectious Diseases Society of America. Crit Care Med 36: 1330-1349, 2008.

Mermel LA, Allon M, Bouza E, Craven DE, Flynn P, O'Grady NP, Raad, II, Rijnders BJ, Sherertz RJ, and Warren DK. Clinical practice guidelines for the diagnosis and management of intravascular catheter-related infection: 2009 Update by the Infectious Diseases Society of America. Clin Infect Dis 49: 1-45, 2009.

Eichacker P, Barochia A, Natanson C, Danner R, Suffredini A, O'Grady N, Kern S. Bundled Care for Septic Shock: An Analysis of Clinical Trials. Crit Care Med 2010 Feb; 38(2):668-78.

Kiringoda R, Thurm AE, Hirschtritt ME, Koziol D, Wesley R, Swedo SE, O'Grady NP, Quezado ZM. Risks of Sedation/Anesthesia for Imaging Studies in Pediatric Research: Eight Years of Experience in a Clinical Research Center. Arch Pediatr Adolesc Med. 2010 Jun; 164(6):554-60.

Kallen AJ, Patel PR, O'Grady NP. Preventing catheter-related bloodstream infections outside the intensive care unit: expanding prevention to new settings. Clin Infect Dis. 2010 Aug 1;51(3):335-41.

Chertow D, O'Grady NP. Central venous catheter related bloodstream infections: Highlights on diagnosis and management. Clev Clin J of Med; 2011 Jan:78 (1):10-17.

O'Grady NP, Alexander M, Burns LA, Dellinger EP, Garland J, Heard SO, LipsettPA, Masur H, Mermel LA, Pearson M, Raad II, Randolph A, Rupp ME, Saint S. 2010 Update: Guideline for the prevention intravascular catheter-related infections. Clin Infect Dis 2011 May;52(9):1087-1099.

Huskins WC, Huckabee C, O'Grady NP, Murray P, Wildasin H, Zimmer L, Walker ME, Sinkowitz-Cochrane RL, Jernigan J, Samore M, Wallace D, Goldmann D. Interventions to reduce transmission of resistant bacteria in intensive care units. N Engl J Med; 2011;364:1407-18.

O'Grady NP. Zero risk for central line-associated bloodstream infections … Is this realistic? Crit Care Med. 2012 Feb;40(2):657-8.

Chertow DS, O'Grady NP. Room for improvement in central venous catheter post-insertion care. Crit Care Med 2012 Jun 40(6)1962-3.

O'Grady NP, Murray P, Ames N. Preventing ventilator-associated pneumonia: Does the evidence support the practice? JAMA 2012 Jun 20;307(23):2534-9.

Miller DL, O'Grady NP. Guidelines for the Prevention of Intravascular Catheter-related Infections: Recommendations Relevant to Interventional Radiology for Venous Catheter Placement and Maintenance. J Vasc Interv Radiol. 2012 Aug;23(8):997-1007.