Biosketch

Bradford Wood is Director of the Center for Interventional Oncology, Chief of Interventional Radiology, and a Senior Investigator with Tenure at NIH. He earned both his undergraduate and graduate degrees from The University of Virginia, then completed an Internship in Internal Medicine, followed by Residency in Diagnostic Radiology at Georgetown University, where he was Chief Resident. He then went on to do double fellowships at Massachusetts General Hospital at Harvard in Abdominal Imaging and Intervention and Vascular & Interventional Radiology, and stayed on staff at Massachusetts General Hospital / Harvard after training.

Dr. Wood was recruited by John Doppman to the NIH in 1998, and has practiced here in Interventional Radiology since. He directed the Interventional Radiology Research Lab from 2004 to present, and was Acting Chief of Radiology - Science and Research and Acting Director of the Molecular Imaging Lab from 2006 to 2008, when he became a Tenured Senior Investigator. He also is an Adjunct Investigator in the National Cancer Institute, and is credentialed in surgery and radiology. He has received both the Clinical Center Director's Award and the NIH Director's Award, and has published widely in Interventional Radiology and in the emerging discipline of Interventional Oncology.

His accolades include All-American in Lacrosse, multiple patents in the field, and pioneering several technologies from the bench to the patient, now in widespread use, including heat-deployed chemotherapy combined with thermal ablation, as well as "Medical GPS" systems with smart needles and devices for multi-modality image-guided procedures. His research interests include drug + device combination therapies, heat deployed nanoparticle vectors, GPS-smart medical devices, navigation in minimally-invasive & image-guided tumor ablation, high intensity focused ultrasound for "drug dose painting", molecular interventions, and the Operating Room of the Future. He was the first physician to perform radiofrequency ablation mono-therapy for kidney tumors in humans in the mid-1990's, the first to use ablation devices plus heat-deployed drugs, and the first to guide ablation with GPS-enabled devices.

He is actively involved in the Society of Interventional Radiology, the Radiological Society of North America, the European Society of Radiology, the Center of Interventional Oncology, the Coalition for Imaging & Bioengineering Research, and the Academy of Radiology Research. He has been a visiting professor and invited faculty at institutions around the world, and has close collaborations with Duke University, Johns Hopkins University, Harvard / Massachusetts General Hospital, Georgetown University Medical Center, Utrecht Medical Center, Eindhoven University of Technology, University Victor Segalen, and Innsbruck Medical University.

Selected Publications

Dr. Wood has published extensively in the field, coauthoring a book on radiology, near 200 manuscripts and chapters, hundreds of scientific abstracts, and numerous patents or patent applications.

BOOKS AND BOOK CHAPTERS

Wood BJ, Wood SD. Radiology (House-officer's Handbook Series). 1st Edition. Williams & Wilkins, Baltimore 1998

Wood BJ, Neeman Z, Kam A: New Technologies in Tumor Ablation. in Tumor Ablation: Principles and Practice. E vanSonnenberg, W McMullen (editors). 2006

Cleary K, Buersmeyer T, Wood BJ, Glossop N: Computer Aided Surgery, in: Wiley Encyclopedia of Biomedical Engineering. Metin Akay (editor), John Wiley and Sons, Inc. 2006

JOURNAL ARTICLES

Wood BJ, Ramkaransingh JR, Fojo T, Walther MM, Libutti SK: Percutaneous Tumor Ablation with Radiofrequency. Cancer 2002; 94:443-451

Wood BJ, Abraham J, Hvizda JL, Alexander HR, Fojo T: Radiofrequency Ablation of Adrenal Tumors and Adrenocortical Carcinoma Metastases. Cancer 2003, 97:554-60

Pingpank JF, Libutti SK, Chang R, Wood BJ, Neeman Z, Kam AW, Figg WD, Zhai SP, Beresneva T, Seidel GD, Alexander HR: Phase I Study Of Hepatic Arterial Melphalan Infusion And Hepatic Venous Hemofiltration Using Percutaneously Placed Catheters In Patients With Unresectable Hepatic Malignancies. J Clin Oncol 2005;23:3465-3474

Wood BJ, Zhang H, Durrani A, Glossop N, Ranjan S, Lindisch D, Levy E, Banovac F, Borgert J, Krueger S, Kruecker J, Viswanathan A, Cleary K: Navigation with Electromagnetic Tracking for Interventional Radiology Procedures: A Feasibility Study. J Vasc Interven Radiol 2005;16: 493-505

Stone M, Wood BJ: Emerging Local Ablation Techniques: in Special Review: Hepatic Malignancies. Seminars in Vascular and Interventional Radiology 2006;23:425-428

Sudheendra D, Barth M, Hegde U, Wilson W, Wood BJ: Radiofrequency Ablation of Lymphoma. Blood 2006;107:1624-1626

Dromi S, Frenkel V, Luk A, Traughber B, Angstadt M, Bur M, Poff J, Xie J, Libutti SK, Li KCP, Wood BJ: Pulsed-high intensity focused ultrasound and low temperature sensitive liposomes for enhanced targeted drug delivery and anti-tumor effect. Clin Cancer Res 2007;13:2722-2727

Wood BJ, Locklin JK, Viswanathan A, Kruecker J, Haemmerich D, Cebral J, Sofer A, Cheng R, McCreedy E, Cleary K, McAuliffe MJ, Glossop N, Yanof J: Technologies for Guidance of Radiofrequency Ablation in the Multimodality Interventional Suite of the Future. J Vasc Interv Radiol 2007;18:9-24

Stone MJ, Frenkel V, Dromi S, Thomas P, Lewis RP, Li KCP, Horne M 3rd, Wood BJ: Pulsed-high intensity focused ultrasound enhanced tPA mediated thrombolysis in a novel in vivo clot model, a pilot study. Thrombosis Research 2007;121:193-202

Krücker J, Xu S, Glossop N, Viswanathan A, Borgert J, Schulz H, Wood BJ: Electromagnetic tracking for thermal ablation and biopsy guidance: clinical evaluation of spatial accuracy. J Vasc Interv Radiol 2007;18:1141-1150

Singh A, Kruecker J, Xu S, Glossop N, Guion P, Ullman K, Choyke P, Wood BJ: Initial Clinical Experience with Real Time Ultrasound-MRI Fusion-Guided Prostate Biopsy. British Journal of Urology International 2008;101:841-845

Dromi SA, Herby S, Walsh M, Dreher M, Xie J, Fry T, Wood BJ: Radiofrequency Ablation Induces Antigen Presenting Cell Infiltration and Amplification of Weak Tumor-Induced Immunity, Radiology 2009; 251:58-66

Venkatesan A, Wood BJ, Gervais D: Percutaneous Ablation in the Kidney. Radiology 2011, in press

Wood BJ, Venkatesan A, Locklin J, Amalou H, Glossop N, , Xu S, Kruecker J: Navigation Systems for Ablation. J Vasc Interv Radiol 2010; 21:S257-63

Kruecker J, Xu S, Venkatesan A, Locklin J, Amalou H, Glossop N, Wood BJ: Clinical Utility of Real-Time Fusion Guidance for Biopsy and Ablation. J Vasc Interv Radiol 2011;22:515-24

Sharma KV, Dreher MR, Tang Y, Pritchard W, Chiesa OA, Karanian J, Perogoy J, Orandi B, Woods D, Donahue D, Esparza J, Jones G, Willis SL, Lewis AL, Wood B: Development of "imageable" beads for transcatheter embolotherapy. J Vasc Interv Radiol 2010;21:865-76

Venkatesan AM, Locklin J, Lai EW, Adams KT, Fojo AT, Pacak K, Wood BJ: Radiofrequency ablation of metastic pheochromocytoma. J Vasc Interv Radiol 2009; 20: 1483-90

Negussie AH, Yarmolenko PS, Partanen A, Ranjan A, Jacobs G, Woods D, Bryant H, Thomasson D, Dewhirst MW, Wood BJ, Dreher MR: Formulation and characterisation of magnetic resonance imageable thermally sensitive liposomes for use with magnetic resonance-guided high intensity focused ultrasound. Int J Hyperthermia. 2011;27:140-55

Pinto PA, Chung PH, Rastinehad AR, Baccala AA, Kruecker J, Xu S, Yan P, Kadoury S, Chua C, Locklin JK, Turkbey B, Shih JH, Gates SP, Buckner C, Bratslavsky G, Linehan WM, Glossop ND, Choyke PL, Wood BJ: MRI/Ultrasound Fusion Guided Prostate Biopsy Improves Cancer Detection Following TRUS Biopsy and Correlates with Multiparametric MRI. J Urology 2011, in press